supranuclear


Also found in: Encyclopedia.

su·pra·nu·cle·ar

(sū'pră-nū'klē-ăr),
1. Above (cranial to) the level of the motor neurons of the spinal or cranial nerves; those pathways the suprasegmental nerve fibers follow to reach the motor cell bodies in the brainstem. As used in clinical neurology, supranuclear indicates disorders of movement caused by destruction or functional impairment of brain structures other than the motor neurons, such as the motor cortex, pyramidal tract, or striate body, for example, supranuclear palsy, as distinguished from the nuclear (or flaccid, or "lower motor neuron") paralysis that results from destruction or functional impairment of the motor neurons or their axons in a peripheral nerve.
2. Region of the cytoplasm apical to the nucleus.

su·pra·nu·cle·ar

(sū'pră-nū'klē-ăr)
Above (cranial to) the level of the motor neurons of the spinal or cranial nerves; the pathways the suprasegmental nerve fibers follow to reach the motor cell bodies in the brainstem; as used in clinical neurology, supranuclear indicates disorders of movement caused by destruction or functional impairment of brain structures other than the motor neurons, such as the motor cortex, pyramidal tract, or striate body, e.g., supranuclear palsy, as distinguished from the nuclear (or flaccid, or "lower motor neuron") paralysis that results from destruction or functional impairment of the motor neurons or their axons in a peripheral nerve.

supranuclear 

In general, referring to nerve fibres situated above a nucleus, such as the abducens, oculomotor and trochlear cranial nerve nuclei.

su·pra·nu·cle·ar

(sū'pră-nū'klē-ăr)
Above (i.e., cranial to) level of motor neurons of spinal or cranial nerves.
References in periodicals archive ?
SUPRANUCLEAR LOCALIZATION OF UNLABELED BNP IN MURINE CARDIOMYOCYTE CELLS
In a recent study of oculomotor function in thirty patients with MSA, (8) excessive square-wave jerks were observed in 21 of the patients, a mild supranuclear gaze palsy in eight patients, a gaze-evoked nystagmus in 12 patients, a positioning down-beat nystagmus in 10 out of 25 patients, mild-moderate saccadic hypometria in 22 patients, impaired smooth pursuit movements in 28 patients, and reduced vestibulo-ocular reflex (VOR) suppression in 16 out of 24 patients.
The supranuclear cytoplasm of the epithelium principal cells of Agouti paca vas deferens was marked by a well-developed endocytotic apparatus, with possible occurrence of adsorptive endocytosis and phase-fluid endocytosis, similarly to the same process previous described in other cells (Goldstein et al.
No outono, tanto nas celulas P (Figura 4a), como nas celulas C (Figura 4b), verificou-se baixa eletrondensidade nucleo-citoplasmatica, havendo em algumas celulas P expansoes do citoplasma supranuclear para o lumen tubular, estando pouco nitidos os limites citoplasmaticos apicais.
Palabras clave: paralisis supranuclear progresiva (PSP), Parkinson plus, parkinsonismo atipico, psicosis.
Suffering from a condition called Progressive Supranuclear Palsy, she knew that the rest of her natural life would be a five or six-year decline into suffering and helplessness.
Dr Turner, who would have celebrated her 67 birthday yesterday, was suffering from Progressive Supranuclear Palsy or PSP, the incurable degenerative disease which killed the actor Dudley Moore in 2002.
This review provides an overview of the epidemiologic evidence for environmental etiologies for neurodegenerative diseases such as Alzheimer disease, Parkinson disease, parkinsonian syndromes (multiple system atrophy and progressive supranuclear palsy), and amyotrophic lateral sclerosis.
The prevalence of dementia varied widely by subtype of dementia: 11% for probable AD (National Institute of Neurological Disorders and Stroke criteria), 11% for frontal lobe dementia, 19% for vascular dementia, 22% for other AD, 23% for Parkinson's disease dementia, and 35% for progressive supranuclear palsy.
1-3) Zolpidem is a short-acting hypnotic GABAergic compound that has been shown to improve rigidity and spasticity in progressive supranuclear palsy and in Parkinson disease.
Dudley - who had the degenerative brain discorder progressive supranuclear palsy - died of pneumonia last week, aged 66, in a modest bungalow in New Jersey.
Moore, who died aged 66 at his home in New Jersey, had been suffering progressive supranuclear palsy for a number of years.