supranuclear


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su·pra·nu·cle·ar

(sū'pră-nū'klē-ăr),
1. Above (cranial to) the level of the motor neurons of the spinal or cranial nerves; those pathways the suprasegmental nerve fibers follow to reach the motor cell bodies in the brainstem. As used in clinical neurology, supranuclear indicates disorders of movement caused by destruction or functional impairment of brain structures other than the motor neurons, such as the motor cortex, pyramidal tract, or striate body, for example, supranuclear palsy, as distinguished from the nuclear (or flaccid, or "lower motor neuron") paralysis that results from destruction or functional impairment of the motor neurons or their axons in a peripheral nerve.
2. Region of the cytoplasm apical to the nucleus.

su·pra·nu·cle·ar

(sū'pră-nū'klē-ăr)
Above (cranial to) the level of the motor neurons of the spinal or cranial nerves; the pathways the suprasegmental nerve fibers follow to reach the motor cell bodies in the brainstem; as used in clinical neurology, supranuclear indicates disorders of movement caused by destruction or functional impairment of brain structures other than the motor neurons, such as the motor cortex, pyramidal tract, or striate body, e.g., supranuclear palsy, as distinguished from the nuclear (or flaccid, or "lower motor neuron") paralysis that results from destruction or functional impairment of the motor neurons or their axons in a peripheral nerve.

supranuclear 

In general, referring to nerve fibres situated above a nucleus, such as the abducens, oculomotor and trochlear cranial nerve nuclei.

su·pra·nu·cle·ar

(sū'pră-nū'klē-ăr)
Above (i.e., cranial to) level of motor neurons of spinal or cranial nerves.
References in periodicals archive ?
In April 2013 Maija Bergs was diagnosed with progressive supranuclear palsy (PSP),a degenerative neuro-diseasethat affects six in every 100,000 people worldwide, and has a life expectancy of only seven years from when symptoms start.
Both disorders can feature eye movement abnormalities, and although the presence of the supranuclear vertical gaze palsy in PSP is diagnostically helpful, it is not universal [8, 9] and maybe absent until quite late in the disease [10].
In our case, vertical supranuclear palsy, prominent postural instability, symmetric rigidity, dementia, and early dysathria are the main characteristics of PSP.
High levels of neurofilament light chain protein (NFL) together with low levels of amyloid-beta 1-42 distinguished progressive supranuclear palsy from PD at baseline as well as 1 year later, after patients had been receiving dopaminergic therapy for months.
Magnetic resonance imaging distinguishes progressive supranuclear palsy from multiple system atrophy.
This report provides comprehensive information on the therapeutic development for Progressive Supranuclear Palsy, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
A support group for people with Parkinson's plus (multiple system atrophy, progressive supranuclear palsy or other atypical Parkinson's diseases) and their partners.
Mrs Hall had a terminal condition called supranuclear palsy.
Both he and his wife, who was suffering with a terminal condition called supranuclear palsy, felt they'd been forced to travel to Zurich as assisted dying remains illegal under UK law.
As noted by Mukhopadhyay and Katzenstein, (2) we found that in most cases, nonspecific labeling with p-Napsin A in mucinous adenocarcinomas had a peculiar supranuclear localization, which contrasted with pan-cytoplasmic finely granular reactivity with m-Napsin A.
Elinor Dunshee Johnson, 86WORCESTER - Elinor Dunshee Johnson, age 86, died on Sunday, March 8, 2015 at the Knollwood Nursing Center after a long battle with Progressive Supranuclear Palsy.She leaves her husband of 66 years, Stanley Murray Johnson, of the Briarwood Retirement Community; her son and daughter-in-law Kenneth & Andrea Johnson of Worcester; her daughter and son-in-law Joanne and John Schmidt of Milford, NH; her grandchildren Emily Finkel and her husband Noah, Gregory Johnson and his wife Stacey, Matthew Schmidt and his fiancee Hannah Gilday, Jonathan Schmidt and his wife Lynse, Kathryn Schmidt; and great grandchildren Madeline and Alden Finkel and Gavin and Trenton Schmidt.
Donations on the day can be made to the Pro-gressive Supranuclear Palsy Association.