We draw the conclusion that the mechanism of aqueous outflow in CLASS may be the filtration from the scleral wound and the percolation to the supraciliary
space, rather than the transscleral percolation to the subconjunctival space, especially in the long-term postoperative observation.
Facsko, "Indapamide-induced transient myopia with supraciliary effusion: case report," BMC Ophthalmology, vol.
Caption: FIGURE 1: Ultrasound biomicroscopy showing, at diagnosis, supraciliary effusion, anterior rotation of the ciliary body and iridocorneal angle narrowing ((a) right eye; (b) left eye) and, three months later, resolution of the effusion and widening of the iridocorneal angle ((c) right eye; (d) left eye).
This may be as a result of an increase in trabecular beam thickness (and possibly stiffness) and an increase in extracellular material within the supraciliary
space in the aged eye.
A 1.5-cm incision is made in the supraciliary
Craven et al., "Two-year COMPASS trial results: Supraciliary Microstenting with phacoemulsification in patients with open-angle glaucoma and cataracts," Ophthalmology, vol.
Ahmed et al., "Initial clinical experience with the CyPass micro-stent: safety and surgical outcomes of a novel Supraciliary Microstent," Journal of Glaucoma, vol.
Ahypoechogenic suprachoroidal space was observed in 67% patients one month after the ciliary body insonification; this indicated an increased uveoscleral outflow through the supraciliary
and suprachoroidal space, in line with histological findings.
The CyPass is a supraciliary
tube designed to create a controlled outflow from the anterior chamber to the suprachoroidal space.