superwarfarinToxicology A warfarin–eg, brodifacoum, bromadiolone, difenacou, which is up to 100-fold more toxic, and has a T1/2 60 times longer than warfarin; ingestion causes severe and prolonged coagulopathy
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
Any of a group of anticoagulant drugs derived from warfarin, used principally for their toxic effect on vermin. Agents in this class have a long half life (weeks to months) compared with warfarin (half life about 1.5 days). They inhibit the synthesis of vitamin K-dependent clotting factors. The principal toxic effect is bleeding. Brodifacoum is a commonly used superwarfarin in the U.S.
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