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su·per·ox·ide dis·mu·tase (SOD),
an enzyme that catalyzes the dismutation reaction, 2O2·- + 2H+ → H2O2 + O2; there are three isozymes of SOD: an extracellular form (ECSOD) that contains copper and zinc, a cytoplasmic form that also contains copper and zinc, and a mitochondrial form that contains manganese; a deficiency of SOD is associated with amyotrophic lateral sclerosis.
Farlex Partner Medical Dictionary © Farlex 2012
An enzyme present in all aerobic organisms which catalyses the reaction O2•– + O2•– + 2H+ = H2O2 + O2. Superoxide dismutase serves to protect the organism against the havoc caused by oxygen free radicals.
Concentrates of superoxide dismutase have been marketed for their claimed ability to reduce ageing and degeneration of tissue, and as a therapy for cataracts, arthritis and other age-related phenomena.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
su·per·ox·ide dis·mu·tase(sū'pĕr-oks'īd dis'myū-tās)
An enzyme that catalyzes the dismutation reaction 2O2·- + 2H+→ H2O2 + O2; a deficiency is associated with amyotrophic lateral sclerosis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
superoxide dismutaseA natural body enzyme that converts the superoxide free radical to hydrogen peroxide, which is then catalyzed to water. The gene for superoxide dismutase is on the long arm of chromosome 21 near the Alzheimer's locus. Brain tissue is highly susceptible to free radical damage. People with Alzheimer's disease have reduced levels of superoxide dismutase.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005