superoxide dismutase


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su·per·ox·ide dis·mu·tase (SOD),

an enzyme that catalyzes the dismutation reaction, 2O2·- + 2H+ → H2O2 + O2; there are three isozymes of SOD: an extracellular form (ECSOD) that contains copper and zinc, a cytoplasmic form that also contains copper and zinc, and a mitochondrial form that contains manganese; a deficiency of SOD is associated with amyotrophic lateral sclerosis.

superoxide dismutase (SOD)

an enzyme composed of metal-containing proteins that converts superoxide radicals into less toxic agents. It is the main enzymatic mechanism for clearing superoxide radicals from the body.

superoxide dismutase

Chemistry
An enzyme present in all aerobic organisms which catalyses the reaction O2•– + O2•–  + 2H+ = H2O2 + O2. Superoxide dismutase serves to protect the organism against the havoc caused by oxygen free radicals.

Fringe medicine
Concentrates of superoxide dismutase have been marketed for their claimed ability to reduce ageing and degeneration of tissue, and as a therapy for cataracts, arthritis and other age-related phenomena.

su·per·ox·ide dis·mu·tase

(sū'pĕr-oks'īd dis'myū-tās)
An enzyme that catalyzes the dismutation reaction 2O2·- + 2H+→ H2O2 + O2; a deficiency is associated with amyotrophic lateral sclerosis.

superoxide dismutase

A natural body enzyme that converts the superoxide free radical to hydrogen peroxide, which is then catalyzed to water. The gene for superoxide dismutase is on the long arm of chromosome 21 near the Alzheimer's locus. Brain tissue is highly susceptible to free radical damage. People with Alzheimer's disease have reduced levels of superoxide dismutase.

superoxide dismutase (sōō·per·ôkˑ·sīd dis·myōōˑ·tās),

n an enzyme that comprises metalloproteins and clears the body of superoxide radicals by converting them into less toxic substances.

superoxide

any compound containing the highly reactive superoxide ion O2, a common intermediate in numerous biological oxidations and an important killing mechanism generated in lysosomes of phagocytes after they have phagocytosed microorganisms.

superoxide dismutase
an enzyme that converts peroxides to two kinds of molecules in different states of oxidation. Present in aerobic bacteria.
References in periodicals archive ?
10 Antioxidant enzymes crucial for protection of the airway against oxidative stress include superoxide dismutase whose activity is reduced in the oxidant-rich environment of the asthmatic airway.
Glutathione peroxidase, superoxide dismutase and catalase genotypes and activities and the progression of chronic kidney disease.
001 ** SD, standard deviation; CAT, catalase; SOD, superoxide dismutase, GPx, glutathione peroxidase.
Adenosine deaminase enzyme activity is increased and negatively correlates with catalase, superoxide dismutase and glutathione peroxidase in patients with Behget's disease: original contributions/clinical and laboratory investigations.
Manganese superoxide dismutase, MnSOD and its mimics," Biochimica et Biophysica Acta (BBA)--Molecular Basis of Disease, vol.
These four amino acids substitutions are responsible for the identity of 97% observed between the buffalo and cattle cooper/zinc superoxide dismutase protein.
Integration of hydrogen peroxide with superoxide dismutase from erythrocytes.
In vivo inhibition of superoxide dismutase in mice by diethyldithiocarbamate.
Immediately after stress, the blood samples were analyzed colorimetrically to estimate serum malondialdehyde and superoxide dismutase by commercially available kits.
The saliva was assessed for superoxide dismutase value by spectrophotometric method using assay kit (Bio Vision Catalog # K335-100).