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su·per·ox·ide dis·mu·tase (SOD),
an enzyme that catalyzes the dismutation reaction, 2O2·- + 2H+ → H2O2 + O2; there are three isozymes of SOD: an extracellular form (ECSOD) that contains copper and zinc, a cytoplasmic form that also contains copper and zinc, and a mitochondrial form that contains manganese; a deficiency of SOD is associated with amyotrophic lateral sclerosis.
superoxide dismutase (SOD)
an enzyme composed of metal-containing proteins that converts superoxide radicals into less toxic agents. It is the main enzymatic mechanism for clearing superoxide radicals from the body.
An enzyme present in all aerobic organisms which catalyses the reaction O2•– + O2•– + 2H+ = H2O2 + O2. Superoxide dismutase serves to protect the organism against the havoc caused by oxygen free radicals.
Concentrates of superoxide dismutase have been marketed for their claimed ability to reduce ageing and degeneration of tissue, and as a therapy for cataracts, arthritis and other age-related phenomena.
su·per·ox·ide dis·mu·tase(sū'pĕr-oks'īd dis'myū-tās)
An enzyme that catalyzes the dismutation reaction 2O2·- + 2H+→ H2O2 + O2; a deficiency is associated with amyotrophic lateral sclerosis.
superoxide dismutaseA natural body enzyme that converts the superoxide free radical to hydrogen peroxide, which is then catalyzed to water. The gene for superoxide dismutase is on the long arm of chromosome 21 near the Alzheimer's locus. Brain tissue is highly susceptible to free radical damage. People with Alzheimer's disease have reduced levels of superoxide dismutase.
superoxide dismutase (sōō·per·ôkˑ·sīd dis·myōōˑ·tās),
n an enzyme that comprises metalloproteins and clears the body of superoxide radicals by converting them into less toxic substances.
any compound containing the highly reactive superoxide ion O2−, a common intermediate in numerous biological oxidations and an important killing mechanism generated in lysosomes of phagocytes after they have phagocytosed microorganisms.
an enzyme that converts peroxides to two kinds of molecules in different states of oxidation. Present in aerobic bacteria.