superoxide dismutase


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su·per·ox·ide dis·mu·tase (SOD),

an enzyme that catalyzes the dismutation reaction, 2O2·- + 2H+ → H2O2 + O2; there are three isozymes of SOD: an extracellular form (ECSOD) that contains copper and zinc, a cytoplasmic form that also contains copper and zinc, and a mitochondrial form that contains manganese; a deficiency of SOD is associated with amyotrophic lateral sclerosis.

superoxide dismutase

Chemistry
An enzyme present in all aerobic organisms which catalyses the reaction O2•– + O2•–  + 2H+ = H2O2 + O2. Superoxide dismutase serves to protect the organism against the havoc caused by oxygen free radicals.

Fringe medicine
Concentrates of superoxide dismutase have been marketed for their claimed ability to reduce ageing and degeneration of tissue, and as a therapy for cataracts, arthritis and other age-related phenomena.

su·per·ox·ide dis·mu·tase

(sū'pĕr-oks'īd dis'myū-tās)
An enzyme that catalyzes the dismutation reaction 2O2·- + 2H+→ H2O2 + O2; a deficiency is associated with amyotrophic lateral sclerosis.

superoxide dismutase

A natural body enzyme that converts the superoxide free radical to hydrogen peroxide, which is then catalyzed to water. The gene for superoxide dismutase is on the long arm of chromosome 21 near the Alzheimer's locus. Brain tissue is highly susceptible to free radical damage. People with Alzheimer's disease have reduced levels of superoxide dismutase.
References in periodicals archive ?
Getzoff, "The role of arginine 143 in the electrostatics and mechanism of Cu,Zn superoxide dismutase: computational and experimental evaluation by mutational analysis," Proteins, vol.
Activities and properties of superoxide dismutase and catalase in the haemolymph of Chlamys farreri.
Glutathione peroxidase, superoxide dismutase and catalase genotypes and activities and the progression of chronic kidney disease.
Cytochrome P450 1A1 and manganese superoxide dismutase gene polymorphisms in Behget's disease.
Changes in activities of superoxide dismutase nitric oxide synthase glutathione-dependent enzymes and the incidence of apoptosis in sheep corpus luteum during the estrous cycle.
Effect of pineal indoles on activities of the antioxidant defense enzymes superoxide dismutase, catalase, and glutathione reductase, and levels of re duced and oxidized glutathione in rat tissues.
Shabrangi.A et al showed that catalase and superoxide dismutase activities of Zea mays L.
Shrivastava, "Synthesis, characterization and superoxide dismutase activity of some ternary copper(II) dipeptide-2,2;-bipyridine, 1,10-phenanthroline and 2,9dimethyl-1,10-phenanthroline complexes," Inorganica Chimica Acta, vol.
jasminoides Ellis via in vitro techniques by utilizing different growth media and various plant hormones and it also aimed to manipulate and evaluate antibacterial, antioxidant, and superoxide dismutase properties of G.
One of these is superoxide dismutase. It protects the pathogens against another cellular defense mechanism: bombarding pathogens with superoxide radicals--highly reactive molecules that cause damage within the pathogens.