superoxide


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to superoxide: hydroxyl radical, superoxide dismutase

superoxide

 [soo″per-ok´sīd]
any compound containing the highly reactive superoxide ion O2, a common intermediate in numerous biological oxidations.

su·per·ox·ide

(sū'pĕr-oks'īd),
An oxygen free radical, O2-, which is toxic to cells.

superoxide

/su·per·ox·ide/ (-ok´sīd) any compound containing the highly reactive and extremely toxic oxygen radical O2−, a common intermediate in numerous biological oxidations.

superoxide

[-ok′sīd]
a common reactive form of oxygen that is formed when molecular oxygen gains a single electron. Superoxide radicals can attack susceptible biological targets, including lipids, proteins, and nucleic acids.

su·per·ox·ide

(sū'pĕr-oks'īd)
An oxygen free radical, O2-. which is toxic to cells.

superoxide,

n a common form of oxygen that is created when molecular oxygen gains a single electron. Superoxide radicals may attack susceptible biologic targets, including lipids, proteins, and nucleic acids.

superoxide

any compound containing the highly reactive superoxide ion O2, a common intermediate in numerous biological oxidations and an important killing mechanism generated in lysosomes of phagocytes after they have phagocytosed microorganisms.

superoxide dismutase
an enzyme that converts peroxides to two kinds of molecules in different states of oxidation. Present in aerobic bacteria.
References in periodicals archive ?
The one most to the point at hand showed the scavenging ability of thiamine for superoxide (generated by the xanthine oxidase/hypoxanthine system) to be dose dependent and able to be driven to completion under the in vitro experimental conditions.
Moreover, approaches that restore mitochondrial function and mitochondrial superoxide production via exercise, caloric restriction and medications should help promote tissue healing.
Although superoxide anion production is essential for bacterial cell killing, the subsequent release of hydrogen peroxide and other additional reactions produces more dangerous ROS, including singlet oxygen and the hydroxyl radical.
When they stimulated the mitochondria by activating a key energy-sensing enzyme called AMPK, superoxide production increased but evidence of diabetic kidney disease markedly declined.
In tests, the researchers found PEG-HCC nanoparticles immediately and completely quenched superoxide activity and allowed the autoregulatory system to quickly regain its balance.
The manganese oxides created by superoxide could possibly be degrading carbon sources in a way that makes them easier for the fungus to feed upon, she speculated.
Within phagocytes, organisms must somehow abrogate the respiratory burst host defence reaction, either by inhibiting its initiation or by resisting the bactericidal action of superoxide and other free radicals produced (10).
The superoxide anion radical scavenging activities of extracts were assayed by the PMS-NADH system.
This research could lead to a modified form of thalidomide that doesn't produce superoxide, but retains its cancer-fighting properties.
The superoxide dismutase 1(SOD1) gene provides instructions for making the enzyme called superoxide dismutase which is normally abundant in cells throughout the body.
The process through which superoxide and hydrogen peroxide are converted into [OH.
Serum lipid peroxide level and blood superoxide dismutase activity in workers with occupational exposure to lead.