The research team suspected that bilirubin's ability to regulate superoxide
originated in its chemical structure, which allows it to grab on to and neutralize the harmful molecule in a way that other antioxidants, such as glutathione and cysteine, cannot.
Optimum pH was determined by assaying the superoxide
dismutase at different pH ranging from 4-8.5 with each 0.5 difference.
Study of effect of examination stress on lipid peroxidation and superoxide
Changes in the superoxide
radical and superoxide
dismutase levels in the uterus of Rattus norvegicus during the estrous cycle and a possible role for superoxide
radical in uterine oedema and cell proliferation at proestrus.
radical-scavenging activity (%) = [1 - (As1 - As2) / As0] x 100, where As0 is the absorbance of the control (distilled water instead of sample); As1 is the absorbance of the test sample mixed with reaction solution, and As2 is the absorbance of the sample alone (distilled water instead of superoxide
radical generating system solution).
is also an intermediate involved in the paramagnetic or diamagnetic transformations of hemoglobin during the transport of oxygen in the activated neuron (7).
Degoul, "The Ala16Val genetic dimorphism modulates the import of human manganese superoxide
dismutase into rat liver mitochondria," Pharmacogenetics, vol.
dismutase, copper-zinc superoxide
dismutase, and manganese superoxide
dismutase are located in the granulosa and theca cells of developing follicles (17).
Conclusion: Levels of serum superoxide
dismutase were elevated with concomitant amplification of copper-zinc superoxide
Richardson, "Electrostatic recognition between superoxide
and copper, zinc superoxide
dismutase," Nature, vol.
The cell responses, that is, membrane permeabilization detected by PI or superoxide
radical accumulation detected by DHE, were monitored at room temperature for 3 h in 15 min intervals using an inverted fluorescence microscope (IX-71, Olympus, Tokyo, Japan) equipped with a CCD camera.
The swelling of nasal mucosa is known to be caused by histamine released from mast cells whose activation is related to a high level intracellular superoxide
, which is nothing but the very substrate of TAT-SOD.