The differential diagnosis of acral fibromyxoma includes superficial angiomyxoma, perineurioma, and myxoid neurofibroma.
Differential diagnosis of myxoid DFSP is diverse and the lesion may be easily confused with a few myxoid neoplasms, such as myxoid neurofibroma, superficial angiomyxoma, myxoid liposarcoma, and low-grade myxofibrosarcoma.
Fibroepithelial stromal polyp, superficial angiomyxoma
, angiomyofibroblastoma, cellular angiofibroma and smooth muscle tumours also need to be considered in the differential diagnoses of a polypoidal mass in the perineum.
(11.) Yuen HK, Cheuk W Luk FO, Wat CS, Auyeung KC, Lam DS, Solitary superficial angiomyxoma
in the eyelid.
reported a case of solitary superficial angiomyxoma
in the eyelid with a similar presentation but follow up was not performed.6
There are 5 entities commonly accepted as myxomas: intramuscular myxoma, juxta articular myxoma, superficial angiomyxoma
(or cutaneous myxoma), aggressive angiomyxoma (usually pelvic and perineal regions) and myxoma of nerve sheath (myxoid neurothekeoma).
[CD34.sup.+] Spindle Cell Neoplasms and Their Differential Diagnoses Fibrohistiocytic and fibroblastic neoplasm Dermatofibrosarcoma protuberans and giant cell fibroblastoma Myxoinflammatory fibroblastic sarcoma Solitary fibrous tumor Giant cell angiofibroma Lipofibromatosis Fibroma Superficial angiomyxoma
Superficial acral fibromyxoma Cellular digital fibroma Cellular angiofibroma Superficial [CD34.sup.+] fibroblastic tumor Neural neoplasms Neurofibroma Nerve sheath myxoma Perineurioma Lipogenic neoplasms Spindle cell lipoma/pleomorphic lipomas Neoplasms of unknown lineage Pleomorphic hyalinizing angiectatic tumor of soft parts Epithelioid sarcoma Table 2.
INTRODUCTION: Superficial angiomyxoma
is a rare benign tumour of dermis and subcutis which was first described by Carney and colleagues in 1986 as a cutaneous myxoma of carney's complex.
The differential diagnosis of aggressive angiomyxoma includes fibroepithelial stromal polyp, angiomyofibroblastoma, myxomas, superficial angiomyxoma
, myxoid neurofibroma, myxoid liposarcoma, and myxofibrosarcoma.
The differential diagnosis of AAM includes angiomyofibroblastoma, superficial angiomyxoma
, fibroepithelial stromal polyps, myxoid lipomatous tumors, and myxoid leiomyoma.
Also in the differential diagnosis is superficial angiomyxoma
. Although this lesion has much microscopic overlap with our case, superficial angiomyxoma
has a characteristic nodular architecture, acellular myxoid clefts, and is grossly well-demarcated; none of these features was seen in our case.
Because of their CD34 positivity and the presence of spindle-shaped and stellate cells embedded in a vascular, basophilic matrix, SAFMs can be confused with superficial angiomyxomas
. In contrast to SAFMs, angiomyxomas are dermal and subcutaneous nodules, which may contain an epithelial component, and affect any body part, especially the head, neck, and trunk.