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Three categories of interventions can be identified (a) interventions on uterine arteries such as laparoscopic uterine artery ligation, uterine artery embolization, pericervical mechanical tourniquet for uterine arteries and hormonal tourniquets such as vasopressin; (b) uterotonics such as ergometrine, oxytocin, misoprostol and sulprostone and (c) myoma dissection techniques which include the use of laser, electrosurgery and chemical dissectors such as sodium-2-mercaptoethanesulfonate (Mesna) (5-10).
During surgery her vital signs were stable despite requiring intravenous carbetocin 100 [micro]g and sulprostone 500 [micro]g for transient uterine atony.
He is also a discoverer of the ultra short acting analgetic/anesthetic remifentanil (ULTIVA(R)), the oral antidiabetic englitazone, the prostaglandin analog sulprostone (Nalador(R)), the use of viral membrane fusion inhibitors such as enfuvirtide (Fuzeon(R)) in combination with other retrovirals in the treatment of HIV infection, and the recent discovery of novel sodium channel blockers such as Parion Sciences 552 for the treatment of cystic fibrosis and chronic bronchitis.
Two prostaglandins used early on in conjunction with RU486 in France, gemeprost and sulprostone, were largely abandoned after one of the four women suffering heart attacks died in 1992.
This short-term decline, which occurred shortly after mifepristone's introduction in 1988, was possibly because in 1991, a death was attributed to sulprostone, the prostaglandin used at that time.
Name of products Acidum pipemidig Atenolol Albendazol Amineptina Aciclovir Acid clavulanic Astemizole Aztreonam Bacampicillin Budesonide Bitolterol mesylate Bromcriptine masylate Bifonazol Cyclosporin Cefadroxil monohydrat Cefotaxime sodium Cyclopirox olamine Cytarabine Hcl Cetraxate Hcl Cefsulodin sodium Cefoperazone Domperidon Estazolam Fentiazac Isoconazol Ipratropium bromide Ifosfamide Ketoconazol Labetalol Hcl Minoxidil Miconazol Metroprolol tartrat Metrizamide Mianserin Hcl Midazolam malfate Metilmicin SO4 Nadolol Nicardipine Hcl Nor floxacin Oxatomide Piroxicam Praziquantel Procaterol Hcl Prazosin Hcl Sisomicin sulfat Sulprostone Tiemonium metil SO4 Tioconazole Vindesine SO4 Vecuronium bromide
Third, researchers in a British study found that the RU 486/oral misoprostol combination results in a higher incidence of ongoing pregnancies (4% of 121 subjects) than RU 486 followed by other prostaglandins, such as geme-prost or sulprostone (0.
He is a discoverer of the ultra-short acting analgetic/anesthetic remifentanil (ULTIVA((R))), the oral anti-diabetic englitazone, and the prostaglandin analog sulprostone.
In the Phase I clinical program, DG041 was found to be well tolerated at all dose levels tested; to provide a dose-dependent reduction in platelet aggregation after stimulation with collagen and sulprostone, and to do so without any significant changes in bleeding time.
In the 1980s, when the RU486 pill was first approved for use in France and Britain, abortionists initially used the prostaglandins gemeprost or sulprostone.
Inhibition of platelet aggregation: DG041 provided a dose-dependent reduction in platelet aggregation after stimulation with collagen and sulprostone, an agonist of prostaglandins E2 (PGE2).
He is the inventor of prazosin (Minipress(R)) and trimazosin (Cardovar(R)), major prototypical agents for the treatment of hypertension and prostatic hyperplasia, and headed the discovery efforts leading to the development of sulprostone (Nalador(R)), a prostaglandin analog licensed to Schering AG for obstetric and gynecological use, and pirbuterol (Maxair(R)), a beta-adrenergic agonist bronchodilator licensed to 3M Pharmaceuticals.
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