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To control bleeding, a Sulprostone infusion was required in addition to 4 packed red blood cells and 4 fresh frozen plasma bags.
EP receptor-specific ligands (EP2 agonist butaprost (free acid), EP3 agonist sulprostone, and EP4 agonist L-902,688) were purchased from Cayman Chemical (Michigan, USA).
Intravaginal, Intramuscular, Intravenous administration of prostaglandin derivatives such as prostaglandin E2 Gel, Sulprostone, Prostaglandin F2 [alpha] have been used for induction of labour with relative success, but requires special care of the patients during treatment to prevent complications.
It has been clearly documented that genetic disruption of EP1 or EP3 receptors blunted the hypertensive response to acute or chronic AngII infusion; the pressor responses to EP1/EP3 agonist sulprostone were abolished in EP1 or EP3 null mice [28-31].
Three categories of interventions can be identified (a) interventions on uterine arteries such as laparoscopic uterine artery ligation, uterine artery embolization, pericervical mechanical tourniquet for uterine arteries and hormonal tourniquets such as vasopressin; (b) uterotonics such as ergometrine, oxytocin, misoprostol and sulprostone and (c) myoma dissection techniques which include the use of laser, electrosurgery and chemical dissectors such as sodium-2-mercaptoethanesulfonate (Mesna) (5-10).
During surgery her vital signs were stable despite requiring intravenous carbetocin 100 [micro]g and sulprostone 500 [micro]g for transient uterine atony.
Two prostaglandins used early on in conjunction with RU486 in France, gemeprost and sulprostone, were largely abandoned after one of the four women suffering heart attacks died in 1992.
This short-term decline, which occurred shortly after mifepristone's introduction in 1988, was possibly because in 1991, a death was attributed to sulprostone, the prostaglandin used at that time.
Table - 4 List of pharmaceutical products, imported without violating patent rights Name of products Acidum pipemidig Atenolol Albendazol Amineptina Aciclovir Acid clavulanic Astemizole Aztreonam Bacampicillin Budesonide Bitolterol mesylate Bromcriptine masylate Bifonazol Cyclosporin Cefadroxil monohydrat Cefotaxime sodium Cyclopirox olamine Cytarabine Hcl Cetraxate Hcl Cefsulodin sodium Cefoperazone Domperidon Estazolam Fentiazac Isoconazol Ipratropium bromide Ifosfamide Ketoconazol Labetalol Hcl Minoxidil Miconazol Metroprolol tartrat Metrizamide Mianserin Hcl Midazolam malfate Metilmicin SO4 Nadolol Nicardipine Hcl Nor floxacin Oxatomide Piroxicam Praziquantel Procaterol Hcl Prazosin Hcl Sisomicin sulfat Sulprostone Tiemonium metil SO4 Tioconazole Vindesine SO4 Vecuronium bromide
Third, researchers in a British study found that the RU 486/oral misoprostol combination results in a higher incidence of ongoing pregnancies (4% of 121 subjects) than RU 486 followed by other prostaglandins, such as geme-prost or sulprostone (0.2%).
In the 1980s, when the RU486 pill was first approved for use in France and Britain, abortionists initially used the prostaglandins gemeprost or sulprostone. However, when they began to encounter problems with their use,1 they began to switch over to misoprostol, a milder prostaglandin marketed by G.D.
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- Sulston, Sir John Edward