sulpiride


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sulpiride

An antipsychotic drug used to treat SCHIZOPHRENIA. Brand names are Dolmatil, Sulparex and Sulpitil.
References in periodicals archive ?
The EPSPs produced by B20 in B8 were blocked by sulpiride and were occluded by dopamine, indicating that they are mediated by dopamine (Diaz-Rios and Miller, 2005).
Most antipsychotic drugs (except sulpiride, amisulpride, risperidone, and paliperidone) are metabolized through the cytochrome P450 (CYP) system.
This is consistent with results obtained in previous studies where sulpiride and [gamma]-tocotrienol SLN enhanced the intestinal permeability of the respective drugs [25, 26].
Although both first- and second-generation antipsychotics can cause hyperprolactinemia, the risk differs between medications, with a higher risk reported in treatments involving amisulpride, sulpiride, and risperidone [8].
Chlorpromazine, haloperidol, levomepromazine, olanzapine, risperidone, sulpiride, and repaglinide were obtained from the National Laboratory of Pharmaceutical Products of Algiers.
Oertel, "Pharmacological characterisation of dopamine overflow in the striatum of the normal and MPTP-treated common marmoset, studied in vivo using fast cyclic voltammetry, nomifensine and sulpiride," Journal of Neuroscience Methods, vol.
There are several additional sulfonamide-based CAIs clinically available for the treatment of the aforementioned diseases, including topiramate, celecoxib (Celebrex), sulpiride (Dogmatil), sulthiame, valdecoxib, zonisamide, irosustat (COUMATE), and esterone sulfamate (EMATE) (Figure 5).
Wang, "The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at serine 307-mediated adipose tissue insulin resistance," Toxicology and Applied Pharmacology, vol.
Furthermore, these antidepressant-like effects were blocked by pretreatment with the dopamine [D.sub.1] receptor antagonist SCH23390 (0.05 mg/kg) and [D.sub.2/3] receptor antagonist sulpiride (50 mg/kg) [18], confirming that the antidepressant-like effects of Apocynum venetum L.
The effects of ropinirole versus vehicle on F3 hiPSC-derived DA neurons were significantly (p < 0.01, Bonferroni's test) attenuated by pretreatment with SB277011-A (50 nM), S33084 (10 nM), and the nonselective D2/D3R antagonist sulpiride (5 [micro]M), but not by the D1R antagonist SCH23390 (1 [micro]M) (Figures 4(a)-4(c)), as supported by the significant two-way ANOVA interaction obtained on the maximal length of dendrites [[F.sub.(4,290)] = 5.4, p < 0.0001], number of primary dendrites [[F.sub.(4,490)] = 4.9, p < 0.0001], and soma area [[F.sub.(4,390)] = 4.3, p <0.001].
As far as sulpiride is concerned, a TdP case has been reported with a therapeutic dose and one of intoxication.
If ECT fails to reduce symptoms or the patient refuses it, topiramate, aripiprazole, or sulpiride may be added to clozapine treatment, said Dr.