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Addition of sulfate groups as esters to preexisting molecules.


Addition of sulfate groups as esters to preexisting molecules.
Synonym(s): sulphation.


n a phase-II detoxification pathway that occurs in the liver and in which compounds that contain sulfur combine with components to remove them from the body.
References in periodicals archive ?
Sinarmas Cepsa has entered into an agreement for acquisition of the Sulphonation / Sulphation chemical plant located in Germany from Gemini Holding.
Due to the incomplete calcination of carbonate phases and the effective sulphation of lime, CFB OSA contains less reactive CaO compared to PF OSA [4, 6].
This feature prevents stratification of the electrolyte and sulphation, which is a major cause of early battery failure.
Sulphation of proteoglycans and intestinal function.
Chemical modifications initially occur in the lumen of the small intestine with cleavage of sugar moieties (when present), after which the aglycones that are released undergo glucuronidation, sulphation and/or methylation (Crozier et al.
Circulating steroid sulphates are thought to be the major source of estradiol in postmenopausal breast tumours and sulphation is a key step in the activation of some dietary pro-carcinogens (Kirck 2001).
The calcination and sulphation kilns are performing to expectation, with scope to further increase the feed rate over the next few weeks.
The calcination and sulphation kilns are key pieces of infrastructure for the Project.
Raven et al 2008, described Paracrine stimulation of IGF-I by ectopic GH production in non-pituitary tissues is suggested by increased basal cartilage sulphation observed in the transgenic salmon.
The metabolic activation of tamoxifen and a-hydroxytamoxifen to DNA-binding species in rat hepatocytes proceeds via sulphation.
Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids.
A number of studies have noted relative deficiencies in detoxification enzymes (superoxide dismutase, paronaxase (34), glutathione peroxidase (35), and sulphation enzymes (36)) and nutrients pertaining to liver detoxifucation pathways (37) (methionine, s-adenosyl methionine, cysteine, glutathione) in children with autistic or autistic-spectrum disorders; these studies may not be applicable to children who have ADHD with heavy metal toxicities.