sulphated polysaccharide

sulphated polysaccharide

Any of a family of antioxidants—e.g., carrageenan, isolated from seaweed, which have therapeutic potential in cyclosporin A-induced hepatotoxicity in rats by reducing lipid peroxidation, and increasing ATPase activity and in treating HIV infection*.  
*By preventing the interaction of epithelial cells and the release of HIV from infected lymphocytes, by coating the cells and virus with a negative charge, making the cells mutually repulsive.
References in periodicals archive ?
Bera, "Immuno-modulation effect of sulphated polysaccharide (porphyran) from Porphyra vietnamensis," International Journal of Biological Macromolecules, vol.
Carrageenan (CG) is a naturally occurring anionic sulphated polysaccharide extracted in 1837 from red seaweed of Rhodophyceae family, predominantly from Chondrus crispus, Eucheuma, Gigartina stellata, Iridaea, Hypnea, Solieria, Agardhiella, and Sarconema [12-14].
Fucoidan, a fucose containing sulphated polysaccharide from brown algae, exhibits antiviral property by inhibiting the attachment of virus to the host cell (156).
Fucoidan, which is extracted from brown seaweed, is a complex sulphated polysaccharide that is mostly composed of L-fucose and sulphated ester groups.
A sulphated polysaccharide (SP-2a) from the brown alga Sargassum patens (Kutz.) Agardh (Sargassaceae) was found to significantly inhibit the in vitro replication of both the acyclovir (ACV)-sensitive and -resistant strains of Herpes simplex virus type 1 (HSV-1), in dose-dependent manners, with 50% inhibitions occurring with 1.5-5.3 [micro]g/ml of the polysaccharide.
Antiviral property and mode of action of a sulphated polysaccharide from Sargassum patiens against Herpes simplex virus type 2.
Bioactivity and applications of sulphated polysaccharides from marine microalgae.
Its properties are derived from its composition, mainly from its iodised matter and sulphated polysaccharides such as fucoids and alginates.
pylori was inhibited by sulphated polysaccharides (heparin and chondroitin sulphates) (Hirmo et al., 1995).