The initial clue that led to the discovery of the RGF peptide family came from the identification of Arabidopsis tyrosylprotein
sulfotransferase (TPST) (described in section 4.
Another group of researchers found that SULT2B1 encodes
sulfotransferase family 2B member 1 and is central to epidermal cholesterol metabolism (Am J Hum Genet.
CYP3A4) and different
sulfotransferase and uridine diphospho-glucuronosyltransferase (UGT) enzymes, as compared to the human small intestine, also makes Caco-2 cells a poor model for studying intestinal metabolism (Gregory et al.
Cytosolic
sulfotransferase (SULT) enzymes metabolize various substrates.
Furthermore, the polymorphism reducing the activity of
sulfotransferase which triggers the development of UTUC is the only genetic etiological factor described in the literature (4).
Characterization of porcine uterine estrogen
sulfotransferase.
Indeed, at least in rats, a
sulfotransferase has been identified for
1N, STM3191, STM4431, fucP, STM0326 and STM1553) showed considerable structural homology with bacterial 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, aryl sulfate
sulfotransferase, acetohydroxy-acid synthase, L-fucose transporter, glycerol dehydratase activator and paired box proteins respectively (Fig.
Ung D, Nagar S (2007) Variable sulfation of dietary polyphenols by recombinant human
sulfotransferase (SULT) 1A1 genetic variants and SULT1E1.
1000] covers phase II detoxification enzymes that include glutathione S-transferse,
sulfotransferase 1a1, betainehomocysteine methyltransferase 2, and UDP glucuronosyltransferease 1A1.
We observed that cytosolic PAPSS2 supported DHEA sulfation by cytoplasmic
sulfotransferase SULT2A1 to a larger extent than cytosolic PAPSS1.
Although relatively little is known about placental EtS transfer, evidence of variable yet substantial fetal
sulfotransferase activity (25) suggests that meconium EtS may be of fetal origin.
