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An isothiocyanate phytochemical present—after conversion from glucoraphanin by myroinase—in cruciferous vegetables (e.g., Brussels sprouts, broccoli, cabbage), which has anticarcinogenic, antimicrobial and antidiabetic activity in experimental systems. 
It stimulates the production of phase-2 enzymes that play a role in detoxifying carcinogens; in rats, sulphoraphane reduces the incidence of mammary tumours induced by dimethylbenzanthracene (DMBA).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Sulforaphane glucosinolate, sulphoraphane Oncology An isothiocyanate phytochemical or 'nutriceutical' in cruciferous vegetables–eg, broccoli, which may prevent CA. See Cruciferous vegetables, Nutriceutical.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


, sulphoraphane (sŭl-fŏr′ă-fān″) [″ + Gr. phainein, to show],


A sulfur-containing compound found in vegetables of the mustard family (Cruciferae). Like other isothiocyanates, it has been shown to prevent cancer in animals.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
In the study, an international team of scientists gave half the group a daily portion of broccoli sprouts and the rest alfalfa sprouts, which do not contain sulforaphane.
Keywords: Sulforaphane; Immunomodulation; Phagocytosis; Tumour necrosis factor-[alpha]
The desire to learn more about sulforaphane led Pierre Coulombe, Ph.D., Professor of Biological Chemistry at Johns Hopkins University School of Medicine in Baltimore, to his colleague, Paul Talalay, M.D., Professor of Pharmacology at the university, who had previously identified sulforaphane as a cancer-preventive agent.
"Our studies suggest that this may be because if you lack the gene you cannot retain any sulforaphane inside your body.
For the next 11 weeks, the mice received either high or low topical doses of sulforaphane or no treatment at all.
Cruciferous vegetables such as broccoli and cabbage are a rich source of sulforaphane, a potent promoter of key detoxifying enzymes.
Researchers at Johns Hopkins University School of Medicine fed rats sulforaphane, another promising plant chemical found in cruciferous vegetables such as broccoli, cauliflower, brussels sprouts and cabbage.
In fact, Brassica Protection Products LLC, based in Baltimore, Md., recently introduced Brassica Tea, which contains sulforaphane (SGS), an antioxidant extracted from broccoli.
Broccoli florets and young seedlings are rich sources of glucoraphanin and its breakdown product sulforaphane, which helps protect mammals against cancer.
A series of studies at Johns Hopkins University demonstrate that Brassica vegetables are rich sources of phase 2 inducers and identify isothiocyanate sulforaphane as the principal phase 2 inducer in broccoli extracts.
Broccoli sprouts (and broccoli) contain an antioxidant compound called sulforaphane glucosinolate, or SGS, a phytochemical that is believed to have strong anticancer properties.
New research has found that the tiny shoots of sprouting broccoli contain a powerful blocking agent known as sulforaphane and sinigrin.