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An isothiocyanate phytochemical present—after conversion from glucoraphanin by myroinase—in cruciferous vegetables (e.g., Brussels sprouts, broccoli, cabbage), which has anticarcinogenic, antimicrobial and antidiabetic activity in experimental systems. 
It stimulates the production of phase-2 enzymes that play a role in detoxifying carcinogens; in rats, sulphoraphane reduces the incidence of mammary tumours induced by dimethylbenzanthracene (DMBA).


Sulforaphane glucosinolate, sulphoraphane Oncology An isothiocyanate phytochemical or 'nutriceutical' in cruciferous vegetables–eg, broccoli, which may prevent CA. See Cruciferous vegetables, Nutriceutical.


, sulphoraphane (sŭl-fŏr′ă-fān″) [″ + Gr. phainein, to show],


A sulfur-containing compound found in vegetables of the mustard family (Cruciferae). Like other isothiocyanates, it has been shown to prevent cancer in animals.
References in periodicals archive ?
Sulforaphane wasn't shielding their bodies directly, but rather increasing their own detox capacity and helping them to expel pollutants.
In the early 1990's, scientists identified glucoraphanin, the naturally occurring compound in broccoli which converts to the antioxidant sulforaphane by enzymes in broccoli (myrosinase) or gut microflora in the body.
The researchers say this means the sulforaphane was absorbed and focused on at-risk tissue.
The activity of sulforaphane is associated with the activation of transcription factor Nrf2, which among other things is also involved in regulation of tumor growth especially in established cancers.
SFX-01 is a synthetic form of sulforaphane, a small molecule that occurs naturally in the vegetable and is part of a group of chemicals found in plants - phytochemicals - that are strong antioxidants and can help regulate some of the body's functions.
uk HEADING STYLE Swiss cress sprout extract, rich in sulforaphane, a powerful antioxidant, is being hailed as the latest answer to pigmentation and BrightLight Intensive Pigmentation & Dark Spot Serum, PS85, is packed with the salad garnish derivative (available next month; www.
Clinical and animal studies showed sulforaphane improved cardiovascular complications through activation of Nrf2.
University of East Anglia scientists found that the ingredient sulforaphane blocks the enzymes that cause osteoarthritis damage.
The company said the new compounds will complement Evgen's molecule SFX-01, a synthetic version of naturally occurring molecule sulforaphane.
15) Cruciferous vegetables such as kale, cabbage, brussels sprouts, and broccoli sprouts contain chemical components, such as sulforaphane (SFN) and indole-3-carbinol (I3C), which have been revealed to be regulators of microRNAs (miRNAs) and inhibitors of histone deacetylases (HDACs) and DNA methyltransferases (DNMTs).
The sprouts are high in sulforaphane, a compound that occurs in broccoli and other cruciferous vegetables whose intake has been associated with protection against environmental carcinogens and several cancers.
This is thanks to an ingredient called sulforaphane, but patients would have to consume substantial amounts on a daily basis for any real benefit.