sulfonylureas


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Related to sulfonylureas: Thiazolidinediones

sul·fo·nyl·u·re·as

(sŭl'fō-nil-yū-rē'ăz),
Derivatives of isopropylthiodiazylsulfanilamide, chemically related to the sulfonamides, which possess hypoglycemic action. Belonging to this series are acetohexamide, azepinamide, chlorpropamide, fluphenmepramide, glymidine, hydroxyhexamide, heptolamide, indylamide, thiohexamide, tolazamide, and tolbutamide.

sul·fo·nyl·u·re·as

(sŭl'fō-nil-yūr'ē-ăz)
Derivatives of isopropylthiodiazylsulfanilamide, chemically related to the sulfonamides, which possess hypoglycemic action. Belonging to this series are acetohexamide, azepinamide, chlorpropamide, fluphenmepramide, glymidine, hydroxyhexamide, heptolamide, indylamide, thiohexamide, tolazamide, and tolbutamide.
Synonym(s): sulphonylureas.

sul·fo·nyl·u·re·as

(sŭl'fō-nil-yūr'ē-ăz)
Derivatives of isopropylthiodiazylsulfanilamide, chemically related to sulfonamides, whichpossess hypoglycemic action (e.g., acetohexamide, tolbutamide).
Synonym(s): sulphonylureas.

sulfonylureas (sul″fənilure´əs),

n a class of medications used in the treatment of diabetes. They cause the pancreas to release more insulin. See also diabetes.
References in periodicals archive ?
On the basis of consistent findings from two randomized, controlled trials including 3,199 total participants (ADOPT and SPREAD-DIM-CAD), a lower risk for cardiovascular mortality was found for metformin monotherapy versus sulfonylurea monotherapy.
On the basis of consistent findings from two randomized, controlled trials including 3,199 total participants (ADOPT and SPREAD-DIMCAD), a lower risk for cardiovascular mortality was found for metformin monotherapy versus sulfonylurea monotherapy.
There was also an increase in the risk for acute myocardial infarction and stroke in some comparisons of sulfonylureas versus other treatments.
2 Yet another possibility for sulfonylurea monotherapy is in markets where sulfonylureas are cheaper than metformin.
1 percent of patients prescribed a sulfonylurea, 39.
He improved gradually within 15 days and this suggests that it is a case of sulfonylurea induced phototoxicity.
With more than two thirds of diabetic patients dying of CV (cardiovascular) causes and millions of patients currently receive sulfonylureas, this question must be resolved with high-quality evidence," he writes.
Overall, patients treated with a sulfonylurea had a mortality hazard ratio of 1.
Previous studies also suggested that the most common combined therapy associates sulfonylureas with metformin.
Recently, however, research has shown some sulfonylureas may be safer than others.
Insulin also helps lower glucose levels in the bloodstream, while sulfonylureas work by stimulating the pancreas to make more insulin.