sulfonylureas


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Related to sulfonylureas: Thiazolidinediones

sul·fo·nyl·u·re·as

(sŭl'fō-nil-yū-rē'ăz),
Derivatives of isopropylthiodiazylsulfanilamide, chemically related to the sulfonamides, which possess hypoglycemic action. Belonging to this series are acetohexamide, azepinamide, chlorpropamide, fluphenmepramide, glymidine, hydroxyhexamide, heptolamide, indylamide, thiohexamide, tolazamide, and tolbutamide.

sul·fo·nyl·u·re·as

(sŭl'fō-nil-yūr'ē-ăz)
Derivatives of isopropylthiodiazylsulfanilamide, chemically related to the sulfonamides, which possess hypoglycemic action. Belonging to this series are acetohexamide, azepinamide, chlorpropamide, fluphenmepramide, glymidine, hydroxyhexamide, heptolamide, indylamide, thiohexamide, tolazamide, and tolbutamide.
Synonym(s): sulphonylureas.

sul·fo·nyl·u·re·as

(sŭl'fō-nil-yūr'ē-ăz)
Derivatives of isopropylthiodiazylsulfanilamide, chemically related to sulfonamides, whichpossess hypoglycemic action (e.g., acetohexamide, tolbutamide).
Synonym(s): sulphonylureas.

sulfonylureas (sul″fənilure´əs),

n a class of medications used in the treatment of diabetes. They cause the pancreas to release more insulin. See also diabetes.
References in periodicals archive ?
For patients who cannot tolerate or have contraindications to metformin, a sulfonylurea is often prescribed as first-line therapy for type 2 diabetes," said Kathleen Dungan, M.
There was also an increase in the risk for acute myocardial infarction and stroke in some comparisons of sulfonylureas versus other treatments.
1 percent of patients prescribed a sulfonylurea, 39.
Metformin users also had a 20% lower risk for any dementia, compared with those on a sulfonylurea such as glyburide.
Investigators found that all three sulfonylureas studied were associated with a more than 50 percent greater risk of death compared to metformin.
Similar to the sulfonylureas, the meglitinides nateglinide (Starlix) and repaglinide (Prandin) are oral insulin secretagogues that are used either alone or with metformin for type 2 diabetes.
Because the drugs act in different ways to lower blood sugar, insulin is often combined with sulfonylureas, metformin and TZDs.
Subjects were then randomized in a double-blind fashion to receive either sulfonylurea plus placebo or sulfonylurea plus 1,000 micrograms of chromium as chromium picolinate for six months.
Clinical trials have shown a benefit to adding exenatide to metformin and sulfonylureas.
In this report, we describe an LC method coupled to ion-trap MS operated in full MS-MS scan mode to screen, identify, and quantify 8 sulfonylureas of interest in clinical toxicology.
The insulin secretagogues include the sulfonylureas (glipizide, glyburide, and glimepiride) and meglitinides (repaglinide and nateglinide).
Sulfonylureas can make your blood sugar too low, which is called hypoglycemia (HY-po-gly-SEE-mee-ah).