sulfonamide

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Related to sulfonamide: sulfanilamide, Sulfonamide drugs

sulfonamide

[sul-fon´ah-mīd]

1. a compound containing the -SO₂NH₂ group.

2. any of a group of structurally related antibiotics that competitively inhibit folic acid synthesis in microorganisms and formerly were bacteriostatic against a wide variety of gram-positive and gram-negative bacteria and some protozoa. Because many microbes are now resistant, sulfonamides have largely been supplanted by more effective and less toxic antibiotics. Called also sulfa drug.

sulfonamide

(sŭl-fŏn′ə-mīd′, -mĭd)

1. Any of a group of organic sulfur compounds containing the radical SO₂NH₂ and including the sulfa drugs.

2. See sulfa drug.

Sulfonamide

A sulfa drug, one of a large group of drugs used to treat bacterial infections.

Mentioned in: Serum Sickness

sulfonamide

Denotes a group of organic derivatives containing SO₂ NH₂. Example: sulfacetamide sodium.

References in periodicals archive ?

Scozzafava, Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents, Med.

Linear Synthesis of {4-[(2-Alkoxy/aralkyloxy-3,5-dichlorophenyl)sulfonyl]-1-piperazinyl}(2-furyl)methanones as Possible Therapeutic Agents

Sulfonamides: Sulfonamides are extensively used for prevention and control of bacterial diseases due to their bacteriostatic and bactericidal effects.

ANTIBIOTIC RESIDUE LEVELS IN CAMEL, CATTLE AND SHEEP TISSUES USING LC-MS/MS METHOD

The proficient activity of first and second compound was the most likely due to occurrence of hydroxyl group at meta position of aniline ring and that of third compound was likely due to the presence of two alkyl groups on aniline ring along with ethyl group attached to nitrogen of sulfonamide.

Pharmacological Evaluation and Synthesis of New Sulfonamides Derivatives Based on 1,4-Benzodioxane

([dagger]) For pregnant women in their first trimester, a 2011 Committee Opinion from the American College of Obstetricians and Gynecologists recommended that sulfonamides and nitrofurantoin may be prescribed only if other antimicrobial therapies are deemed clinically inappropriate (4).

Antibiotics Dispensed to Privately Insured Pregnant Women with Urinary Tract Infections--United States, 2014

Multiple reaction monitoring (MRM) was applied, and two product ions (for quantification and confirmation transition) were selected for each sulfonamide. The mass detector settings and gradient values for individual analytes are shown in Table 2.

Sulfonamide Residues: Honey Quality in the Czech Market

The sulfonamide and trimethoprim identity was confirmed by obtaining the accurate mass of the protonated molecular ion, as well as by the consideration of fragment ions in order to obtain the identification points (IPs) according to Commission Decision 2002/657/EC [22] (Table 1).

Multiresidue Method for Quantification of Sulfonamides and Trimethoprim in Tilapia Fillet by Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry Using QuEChERS for Sample Preparation

To detection of quinolones and sulfonamides residues, 99 samples of unpasteurized milk donated by a dairy industry were analyzed.

Antibiotic residues in pasteurized and unpasteurized milk marketed in southwest of Parana, Brazil/Residuos de antibioticos no leite pasteurizado e nao pasteurizado comercializados no sudoeste do Parana, Brasil

Synthesis and antibacterial activity of sulfonamide derivatives at C-8 alkyl chain of anacardic acid mixture isolated from a natural product cashew nut shell liquid (CNSL).

Synthesis, Antibacterial and Lipoxygenase Inhibition Studies of N-(Alkyl/aralkyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methylbenzenesulfonamides/N-(Alkil/aralkil)-N-(2,3-dihidro-1,4-benzodioksin-6-il)-4-metilbenzensulfonamitlerin Sentezi ile Antibakteriyel ve Lipoksijenaz Inhibitor Ozellikleri

[F.sub.LUMO], the hydrogen bond acceptor (HA), the hydrogen bond donor (HD), (logP), and R index are the descriptors dependent on the anticancer activity of a sulfonamide.

Organic Compounds Based on (E)-N-Aryl-2-ethene-sulfonamide as Microtubule Targeted Agents in Prostate Cancer: QSAR Study

The aim of the present study was to use an eluent additive 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) to improve LC separation significantly with alternative selectivity in C18 stationary phase and enhance MS detection of fluoroquinolones (FQs) and sulfonamides (SAs) in small concentration levels to quantify them in food plant samples.

Simultaneous Determination of Fluoroquinolones and Sulfonamides Originating from Sewage Sludge Compost

The model assumed that first-line empirical treatment of uUTIs would consist of one of the antibiotics currently reimbursed by the Ontario Drug Benefit Program (ODBP) [44] and recommended by recent guidelines [5, 13, 14] for the treatment uUTIs: sulfonamides (TMP/SMX DS 800 mg/160 mg, TMP 100 mg, or TMP 200 mg), fluoroquinolones (Cipro[R] XL[TM] 500 mg, ciprofloxacin 250 mg [generic], or norfloxacin 400 mg), or nitrofurantoins (MacroBID[R] 100 mg, nitrofurantoin 50 mg [generic], or nitrofurantoin 100 mg [generic]).

Cost-Effectiveness Analysis of Fosfomycin for Treatment of Uncomplicated Urinary Tract Infections in Ontario

Pilar Tornero and colleagues used patch testing and control oral challenge in patients with previous fixed drug eruptions to trimethoprim-sulfamethoxazole or an unknown sulfonamide (Contact Dermatitis 2004;51:57-62).