sulfobromophthalein

sulfobromophthalein

 [sul″fo-bro″mo-thal´ēn]
a sulfur- and bromine-containing compound, used as the sodium salt in liver function tests; see also bromsulphalein.
sulfobromophthalein test a liver function test in which the dye sulfobromophthalein sodium is introduced into the circulatory system and a blood sample is withdrawn 30 or 45 minutes later, depending on the dose injected. The parenchymal cells remove almost all of the dye within this time if they are functioning normally. The rate of removal is influenced by the blood flow through the portal circulation, the functioning capacity of the liver cells, and the patency of the biliary tract.
References in periodicals archive ?
Klaassen, "Nrf2 activation enhances biliary excretion of sulfobromophthalein by inducing glutathione-S-transferase activity," Toxicological Sciences, vol.
J., Metabolism and biliary excretion of sulfobromophthalein by rainbow trout (Salmo gairdneri).
Enzymatic assays with 1-Chloro 2,4-dinitrobenzene (CDNB), ethacrynic acid (EA), sulfobromophthalein (BSP), p-nitrobenzyl chloride (NBC), trans-4-phenyl-3-buten-2-one (PBO) [16], and 3,4-Dichloronitrobenzene (DCNB) [17] were determined according to protocols described in the respective articles.
Substrate Specific activity ([micro]mol/min/mg) GST1 GST2 Ethacrynic acid 24.91 [+ or -] 1.24 15.71 [+ or -] 2.53 Hydrogen peroxide 3.93 [+ or -] 0.38 nd 1-Chloro-2,4- 0.61 [+ or -] 0.122 0.542 [+ or -] 0.127 dinitrobenzene trans, trans-Hepta-2, 0.11 [+ or -] 0.02 0.084 [+ or -] 0.01 4-dienal 1,2-Dichloro-4- Nd nd nitrobenzene p-nitrophenyl chloride Nd nd Sulfobromophthalein Nd nd trans-4-Phenyl-3- Nd nd butene-2-one Cumene hydroperoxide Nd nd Dichloromethane Nd nd nd: not detected.
The lowest molecular weight fraction was identified as fatty acid binding protein as judged by its relative elution volume in Sephadex G-75, its binding characteristics to sulfobromophthalein, and palmitic acid binding inhibition by flavaspidic acid.
Sulfobromophthalein inhibition of glutathione and methylmercury secretion into bile.
Effect of estradiol on plasma disappearance rate of sulfobromophthalein in man.
The impairment of sulfobromophthalein sodium excretion, especially in multiple pregnancy, is taken placidly.
Binding of sulfobromophthalein (BSP) sodium and indocyanine green by plasma [alpha]-1 lipoproteins.
The plasma removal of indocyanine green and sulfobromophthalein: effect of dosage and blocking agents.