sulfatide


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sulfatide

 [sul´fah-tīd]
any of a class of cerebroside sulfuric esters.

sulfatide

/sul·fa·tide/ (sul´fah-tīd) any of a class of cerebroside sulfuric esters; they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.

sulfatide

(sŭl′fă-tīd)
Any cerebroside with a sulfate radical esterified to the galactose.

sulfatide

any of a class of cerebroside sulfuric esters.
References in periodicals archive ?
Sulfatide levels correlate with severity of neuropathy in metachromatic leukodystrophy.
Metachromatic Leukodystrophy gets its name from the metachromatic granules which are formed as a result of the accumulation of galactosyl and lactosyl sulfatide substrate deposits.
2002) A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation.
The most striking example is sulfatide that has the unique property of binding and activating T cells restricted to all CD1 isoforms [14].
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: Potential role in disease pathogenesis.
4,7) The CssA interacted with the host cell fibronectin while CssB binds to cell surface sulfatide.
These genetically modified HSC begin producing ARSA, which leads to digesting sulfatide and avoiding neurodegeneration.
developed microarrays of lipids present in the myelin sheath, including ganglioside, sulfatide, cerebroside, sphingomyelin, and total brain lipid fractions (13).
It is a metabolic disorder of the nervous system, which results in an accumulation of sulfatide in tissues that manifests as mental deterioration and severe central nervous system disturbances.
In addition, tandem mass spectrometry has been used to screen for other metabolites such as urine oligosaccharides,(4) sulfatide,(5) very long chain fatty acids,(6) long chain bile acids,(7) methylmalonic acid,(8) and for the investigation of porphyrias(9) and screening for patients at risk of inherited disorders of purine and pyrimidine metabolism.
The study identified sulfatide as a possible target of the immune attack.
Subjects covered include the biochemical diagnosis of Gaucher disease, modulation of fatty acid molecular species in sulfatide and its precursor, the role of gangliosides in cellular interactions with microbe and immune cell activation, and the importance of gangliosides in mast cell biology.