sulfanilamide


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sulfanilamide

 [sul″fah-nil´ah-mīd]
a potent antibacterial compound. Although replaced as a systemic agent by more effective and less toxic derivatives, and by antibiotics; it is still used vaginally in the treatment of vulvovaginal candidiasis.

sul·fa·nil·a·mide

(sŭl'fă-nil'ă-mīd),
The first sulfonamide used for its chemotherapeutic effect in infections.

sulfanilamide

(sŭl′fə-nĭl′ə-mīd′, -mĭd)
n.
A white, odorless crystalline sulfonamide, C6H8N2SO2, used in the treatment of various bacterial infections.

sulfanilamide

[sul′fah-nil′ah-mīd]
a potent antibacterial compound. Although replaced as a systemic agent by more effective and less toxic derivatives and by antibiotics, it is still used vaginally in the treatment of vulvovaginal candidiasis.

sulfanilamide

a potent antibacterial compound, the first of the sulfonamides, the first real antibacterial and the drug that opened the door into the antibiotic era.
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References in periodicals archive ?
toxicity and increased resistance to sulfanilamides.
Abstracts and program for the Annual Meeting of the Georgia Academy of Science, 2017
Prediction of sulfanilamide solubility in dioxane-water mixtures.
Solvatacion preferencial de algunas sulfonamidas en mezclas cosolventes 1,4-dioxano + agua a 298,15 K segun el metodo de las integrales inversas de Kirkwood-Buff
The sulfa drugs sulfanilamide, sulfapyridine, and sulfathizole prepared by organic chemistry students were tested in microbiology experiments.
Abstracts of papers presented at the 2012 Collegiate meetings
1938) Pathologic effects of elixir of sulfanilamide (diethylene glycol poisoning).
Drogas potenciadoras para la busqueda de la perfeccion
The Griess reagent consists of sulfanilamide (58 mM in 3 M HCl) and N-1-naphtylethylenediamine (722 [micro]M).
Lipid peroxidation and nitric oxide levels in male smokers' spermatozoa and their relation with sperm motility
In 1937, more than a hundred people died in the United States as a result of using a drug formulated with a toxic solvent in what came to be known as the Elixir Sulfanilamide Tragedy.
The Drug Debacle A Way Forward
Carol Ballentine, Taste of Raspberries, Taste of Death: The 1937 Elixir Sulfanilamide Incident, FDA CONSUMER, June 1981, available at http://www.
Reputation and Power: Organizational Image and Pharmaceutical Regulation at the FDA
Rocky was treated for sulfanilamide, Bactrim, and Septra (found in meats which putatively block sulfur metabolism in the whole body), 23 different mercury salts, cadmium diazinon, DDT-DDE, insulin, pancreas, benzene, xylene, toluene, dioxin, HGH, PCBs, heptachlor, testosterone, formaldehyde-formic acid, petroleum, atrazine, carbon tetrachloride, methyl ethyl ketone, glucagon, leptin, liver, and heart.
Thirty years of progress in cardiovascular health
For example, the predecessor of the Food and Drug Administration was empowered to demand premarket approval of drags as a result of poisoning by elixir sulfanilamide in 1937.
Markets, tort law, and regulation to achieve safety
24) See Deaths Following Elixir of Sulfanilamide-Massengill, 109 JAMA 1367, 1367 (1937); see also Carol Ballentine, Taste of Raspberries, Taste of Death: The 1937 Elixir Sulfanilamide Incident, FDA CONSUMER, June 1981, at 18, 21.
FDA preemption of drug and device labeling: who should decide what goes on a drug label?
5 by coupling diazotized sulfanilamide with N-(1-naphthyl)-ethylenediamine dihydrochloride (NED dihydrochloride).
Physicochemical Assessment of Surface and Groundwater Quality of the Greater Chittagong Region of Bangladesh
Massengill's Elixir Sulfanilamide hit the market in the fall of 1937.
The conquering bureaucracy: a new history of the FDA shows how regulators entrenched and extended their own power

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