sulfamethoxazole


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sulfamethoxazole

 [sul″fah-meth-ok´sah-zōl]
a sulfonamide used as an antibacterial, especially for the treatment of acute urinary tract infections, and as an antiprotozoal; administered orally. Its use has declined as organisms have increasingly developed resistance to it, and when used it is usually combined with another agent such as trimethoprim.

sul·fa·meth·ox·a·zole

(sŭl'fă-meth-ok'să-zōl),
A sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption from the gastrointestinal tract and urinary excretion. Often used in combination with trimethoprim (that is, SMX-TMP).

sulfamethoxazole

/sul·fa·meth·ox·a·zole/ (-meth-ok´sah-zōl) a sulfonamideantibacterial and antiprotozoal, particularly used in acute urinary tract infections.

sulfamethoxazole

(sŭl′fə-mə-thŏk′sə-zōl)
n.
A sulfonamide antibiotic, C10H11N3O3S, that is used especially in combination with trimethoprim to treat bacterial urinary tract infections, other bacterial infections, and infections caused by certain fungi and parasites.

sulfamethoxazole

[sul′fəmethok′səzōl]
a sulfonamide antibacterial.
indications It is prescribed in the treatment of otitis media, prostatitis, epididymitis, bronchitis, and certain urinary tract infections.
contraindications It is not given during the last trimester of pregnancy, during lactation, or to children less than 2 months of age. Known hypersensitivity to this drug or to other sulfonamides prohibits its use.
adverse effects Among the more serious adverse effects are crystalluria and rash, fever, and other allergic reactions.

sulfamethoxazole

Pharmacology A sulfonamide used for UTIs or, with trimethoprim for PCP. See Pneumocystis carinii pneumonia, Trimethoprim-sulfamethoxazole.

sulfamethoxazole/trimethoprim

Bactrim, see there.

sul·fa·meth·ox·a·zole

(sŭlfă-me-thoksă-zōl)
A sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption and urinary excretion. Often used with trimethoprim (i.e., SMX-TMP).

sul·fa·meth·ox·a·zole

(SMX) (sŭlfă-me-thoksă-zōl)
Sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption from gastrointestinal tract and urinary excretion. Often used in combination with trimethoprim (i.e., SMX-TMP).

sulfamethoxazole (sul´fəmethok´-səzōl),

n brand names: Gamazole, Gantanol, Urabak;
drug class: sulfonamide;
action: interferes with bacterial biosynthesis of proteins by competitive antagonism of paraaminobenzoic acid (PABA);
uses: treatment of urinary tract infections, lymphogranuloma venereum, and systemic infections.

sulfamethoxazole

an antibacterial sulfonamide, especially useful in acute urinary tract infections and in infections of wounds and soft tissues. Commonly combined with trimethoprim.
References in periodicals archive ?
Reddy's success with Sulfamethoxazole is not unique, though it bucks the prevailing trend.
In summary, sulfamethoxazole produces a small peak at the anodal site of the albumin fraction with CZE.
A small-scale investigation has evaluated the usefulness of hapten carrier conjugates of sulfamethoxazole for skin testing.
The passage of trimethoprim/ sulfamethoxazole into breast milk and its significance.
Using these figures for a "base case" analysis, he concluded that probability rates for each drug having activity against an empiric skin infection were 95% for clindamycin, 89% for trimethoprim / sulfamethoxazole, and 28% for cephalexin.
The patient was discharged with instructions to take trrimethoprim/ sulfamethoxazole (1,920 mg orally 2x/d) and doxycycline (100 mg orally 2x/d) for an additional 20 weeks.
Yun's patient was started on 160 mg oral trimethoprim and 800 mg oral sulfamethoxazole daily in two divided doses for 3 months.
The girl was treated with trimethoprim / sulfamethoxazole for 3 days and had recovered after 5 days.
aureus infection was resistant to vancomycin, but none were resistant to either rifampin or trimethoprim / sulfamethoxazole.
The strain was sensitive to penicillin, ampicillin, gentamicin, rifampin, vancomycin, teicoplanin, tetracycline, sulfamethoxazole, trimethoprim, fusidic acid, ciprofloxacin, and norfloxacin and resistant to erythromycin, lincomycin, and nitrofurantoin.
In addition, both strains were found to be d-tartrate-fermenting (dT+) biovars (4), susceptible to ampicillin, amoxicillin-clavulanic acid, cephalothin, ceftazidime, gentamicin, streptomycin, chloramphenicol, tetracycline, neomycin, nalidixic acid, norfloxacin, and ciprofloxacin and resistant to sulfamethoxazole and co-trimoxazole.
70 * sulfamethoxazole trimethoprim and 800 mg su- lfamethoxazole once a day for 3 days trimethoprim 100 mg b.