sulfamethoxazole


Also found in: Dictionary, Thesaurus, Acronyms, Wikipedia.

sulfamethoxazole

 [sul″fah-meth-ok´sah-zōl]
a sulfonamide used as an antibacterial, especially for the treatment of acute urinary tract infections, and as an antiprotozoal; administered orally. Its use has declined as organisms have increasingly developed resistance to it, and when used it is usually combined with another agent such as trimethoprim.

sul·fa·meth·ox·a·zole

(sŭl'fă-meth-ok'să-zōl),
A sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption from the gastrointestinal tract and urinary excretion. Often used in combination with trimethoprim (that is, SMX-TMP).

sulfamethoxazole

/sul·fa·meth·ox·a·zole/ (-meth-ok´sah-zōl) a sulfonamideantibacterial and antiprotozoal, particularly used in acute urinary tract infections.

sulfamethoxazole

(sŭl′fə-mə-thŏk′sə-zōl)
n.
A sulfonamide antibiotic, C10H11N3O3S, that is used especially in combination with trimethoprim to treat bacterial urinary tract infections, other bacterial infections, and infections caused by certain fungi and parasites.

sulfamethoxazole

[sul′fəmethok′səzōl]
a sulfonamide antibacterial.
indications It is prescribed in the treatment of otitis media, prostatitis, epididymitis, bronchitis, and certain urinary tract infections.
contraindications It is not given during the last trimester of pregnancy, during lactation, or to children less than 2 months of age. Known hypersensitivity to this drug or to other sulfonamides prohibits its use.
adverse effects Among the more serious adverse effects are crystalluria and rash, fever, and other allergic reactions.

sulfamethoxazole

Pharmacology A sulfonamide used for UTIs or, with trimethoprim for PCP. See Pneumocystis carinii pneumonia, Trimethoprim-sulfamethoxazole.

sulfamethoxazole/trimethoprim

Bactrim, see there.

sul·fa·meth·ox·a·zole

(sŭlfă-me-thoksă-zōl)
A sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption and urinary excretion. Often used with trimethoprim (i.e., SMX-TMP).

sul·fa·meth·ox·a·zole

(SMX) (sŭlfă-me-thoksă-zōl)
Sulfonamide related chemically to sulfisoxazole, with a similar antibacterial spectrum, but a slower rate of absorption from gastrointestinal tract and urinary excretion. Often used in combination with trimethoprim (i.e., SMX-TMP).

sulfamethoxazole (sul´fəmethok´-səzōl),

n brand names: Gamazole, Gantanol, Urabak;
drug class: sulfonamide;
action: interferes with bacterial biosynthesis of proteins by competitive antagonism of paraaminobenzoic acid (PABA);
uses: treatment of urinary tract infections, lymphogranuloma venereum, and systemic infections.

sulfamethoxazole

an antibacterial sulfonamide, especially useful in acute urinary tract infections and in infections of wounds and soft tissues. Commonly combined with trimethoprim.
References in periodicals archive ?
In summary, sulfamethoxazole produces a small peak at the anodal site of the albumin fraction with CZE.
A small-scale investigation has evaluated the usefulness of hapten carrier conjugates of sulfamethoxazole for skin testing.
Trimethoprim is a commonly prescribed antimicrobial agent used in combination with sulfamethoxazole (co-trimoxazole) for the treatment of diarrheal diseases.
A new type of conjugative transposon encodes resistance to sulfamethoxazole, trimethoprim, and streptomycin in Vibrio cholerae O139.
We found antimicrobial catheter lock solutions with active agents such as trimethoprim/ sulfamethoxazole or minocycline to be effective against Nocardia biofilm.
Resistance to trimethoprim/ sulfamethoxazole was 59% in Nigeria, compared with 71% in Ghana.
MICs were determined for ampicillin, cefotaxime, ceftiofur, chloramphenicol, ciprofloxacin, florfenicol, gentamicin, nalidixic acid, kanamycin, streptomycin, sulfamethoxazole, tetracycline, and trimethoprim.
Of the 1,170 isolates that were analyzed, 93% were resistant to at least one antimicrobial agent, including ampicillin (79% of isolates), streptomycin (56%), sulfamethoxazole (56%), tetracycline (53%), and combined trimethoprim and sulfamethoxazole (51%).
NASDAQ: CRTQ) has initiated preclinical development of a series of compounds to treat allergy to sulfamethoxazole (SMX) in AIDS patients, announced David K.
25 mg/L for sulfamethoxazole (Etest; AB Biodisk, Solna, Sweden).
Of 13 antimicrobial drug-resistant phenotypes identified, the most often observed phenotype (21/44) was resistance to amoxicillin-clavulanic acid, ampicillin, chloramphenicol, ciprofloxacin, gentamicin, nalidixic acid, sulfamethoxazole, streptomycin, trimethoprim sulfamethoxazole, and tetracycline (R-type AcAmCCpGNSStSxtT).
The combination of sulfamethoxazole and trimethoprim is probably the best choice for antibiotic prophylaxis, because it's safe for use in pregnancy.