MRM transitions of the antibiotics were as following: chlortetracycline, m/z 479.4 a 444.1 and m/z 479.4 a 462.1; ciprofloxacin, m/z 332.5 a 314.5 and m/z 332.5 a 231.4; enrofloxacin, m/z 360.0 a 432.0 and m/z 360.0 a 286.0; sulfamethazine
, m/z 279.1 a 92.0 and m/z 279.1 a 124.0; sulfaquinoxaline, m/z 301.0 a 156.0 and m/z 301.0 a 108.0; tetracycline m/z 445.4 a 154.0 and m/z 445.4 a 410.2; oxytetracycline m/z 461.2 a 426.2 and m/z 461.2 a 443.1; erythromycin m/z 735.1 a 158.2 and m/z 735.1 a 576.2; tylosin, m/z 916.5 a 174.0 and m/z 916.5 a 100.9, were the qualifier and quantifier ions, respectively (Han et al., 2015).
They also saw that sulfamethazine
in particular was disappearing five times faster than the other antibiotics.
Other kits are already available for detection of drug residues, such as chloramphenicol, sulfonamides, ractopamine, streptomycin, sulfamethazine
and sulfadiazine, and determination of vitamin content.
In addition to the antituberculosis agent isoniazid (1), the first NAT2 substrate discovered, numerous other chemicals possessing a primary aromatic amine or hydrazine group, such as sulfamethazine
, procainamide, hydralazine (2), dapsone, nitrazepam, and caffeine, are metabolized by this enzyme.
Analyte Retention Time (minute) Corn oil 10.9 Bis (2-ethylhexyl) phthalate 12.9 Methoxychlor 14.5 Sulfamerazine 15.0 Chloramphenicol 15.1 Sulfaquinoxaline 15.2 * NorBoxacin 15.2 Sulfamethazine
15.5 Sulfadiazine 15.8 Perylene 18.5 Sulfur 22.5 * OI Analytical P.O.
Determination of Sulfamethazine
in Bovine and Porcine Tissues by Reversed-Phase Liquid Chromatography.
Specifically, no sulfamethazine
(a drug suspected of causing cancer that is no longer permitted for use in milk cows) or other potentially dangerous drugs were found in the 14-city survey of milk.
In March 1988, nearly three-quarters of the milk samples it tested (in a small survey) contained the drug sulfamethazine
, which causes cancer in animals.
 examined UHT and pasteurized milks to verify the presence of residues of tetracyclines, sulfonamides, sulfamethazine
, and quinolone.
At its 40th session, the Codex Alimentarius Commission reported a maximum residue limit (MRL) value for sulfadimidine (sulfamethazine
) of 100 [micro]g*[kg.sup.-1] in muscle, for species not specified .
uptake by plants from manure-amended soil," Journal of Environmental Quality, vol.
Antimicrobials residues of enrofloxacin, sulfamethazine
, sulfadimethoxine, sulfadiazine, chloramphenicol, and sulfathiazole, complying with the maximum residue limits (MRL) established for eggs , were selected and tested.