sulfadiazine


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Related to sulfadiazine: Silver sulfadiazine

sulfadiazine

 [sul″fah-di´ah-zēn]
a sulfonamide used, frequently in combination with other sulfonamides, in the treatment of infections due to susceptible organisms, including nocardiosis, toxoplasmosis, otitis media caused by susceptible strains of Haemophilus influenzae,streptococci, and pneumococci, and malaria caused by chloroquine-resistant Plasmodium falciparum. It is administered orally as the base or intravenously as the sodium salt. See also silver sulfadiazine.
sodium sulfadiazine an antibacterial compound used intravenously.

sul·fa·di·a·zine

(sŭl'fă-dī'ă-zēn),
One of a group of diazine derivatives of sulfanilamide, the pyrimidine analogue of sulfapyridine and sulfathiazole; one of the components of the triple sulfonamide mixture. It is an inhibitor of bacterial folic acid synthesis, which has been highly effective against pneumococcal, staphylococcal, and streptococcal infections, against infections with Escherichia coli and Klebsiella pneumoniae, and in acute gonococcal arthritis; sulfadiazine sodium has the same uses.

sulfadiazine

(sŭl′fə-dī′ə-zēn′)
n.
A sulfa drug, C10H10N4O2S, used in the treatment of toxoplasmosis and other infections.

sulfadiazine

Pharmacology A sulfonamide used with pyrimethamine to treat toxoplasmosis in AIDS  and meningitis Adverse effects BM suppression, crystallization in urinary tract, leading to kidney failure. See Sulfonamide.

sul·fa·di·a·zine

(sŭl'fă-dī'ă-zēn)
Diazine derivative of sulfanilamide; inhibitor of bacterial folic acid synthesis, which has been highly effective against pneumococcal, staphylococcal, and streptococcal infections, against infections with Escherichia coli and Klebsiella pneumoniae, and in acute gonococcal arthritis.

sul·fa·di·a·zine

(sŭl'fă-dī'ă-zēn)
Inhibitor of bacterial folic acid synthesis; highly effective against pneumococcal, staphylococcal, and streptococcal infections, against infections with Escherichia coli and Klebsiella pneumoniae.
References in periodicals archive ?
Aloe versus silver sulfadiazine creams for second-degree burns: a randomized controlled study.
The control plates were prepared without addition of any drug for comparing the inhibitory effect of the standard silver sulfadiazine and the functionalized AgNP.
Six samples were positive for sulfathiazole in the range of 5-9 [micro]g/kg and three for sulfadiazine at 13-100 [micro]g/kg.
Even though formal acne studies have not been performed with silver sulfadiazine, it has long been used "off-label" for this purpose.
Roi et al., "Comparing effects of Silver sulfadiazine, sucralfate and brassica oleracea extract on burn wound healing," Life Science Journal, vol.
Yaman, "Efects of Nigella sativa and silver sulfadiazine on burn wound healing in rats," Veterinarni Medicina, vol.
Clinical toxicity has been well described in both adults and children receiving PG-containing medications including lorazepam, diazepam, pentobarbital, trimethoprim-sulfamethoxazole, esmolol, phenytoin, phenobarbital, etomidate, nitroglycerin, multivitamin preparations, and silver sulfadiazine [2].
Nowadays, prescription drugs such as sulfadiazine silver and mafenide, which are effective in relieving symptoms and promoting healing, are widely used in burn.
(2009) have worked on developing a cream of sericin (8% w/w) in combination with silver sulfadiazine (SSD); the authors took advantage of these ingredients by promoting the collagen and antimicrobial properties, respectively.