A hypothesis is that these antibiotics, particularly the
sulfas, might induce changes in the microbiome (bacteria in the intestines and urinary tract), or in macronutrient metabolism.
The man who more or less discovered
sulfa drugs was German chemist and pathologist Gerhard Domagk (1895-1964), director of research for I.G.
There has always been concern that there is a possibility of increased risk of drug reactions in patients who receive a
sulfa nonantibiotic, and frequently prescriptions for these medicines are not filled by pharmacies without directly confirming the intent by speaking with the pre-scriber.
To summarize, treatment of the acute mountain sickness in individuals with
sulfa allergy in the light of Consensus Statement UIAA vol.
But further research has suggested otherwise, finding no increased risk of allergic reactions among patients with self-reported
sulfa allergies who took furosemide and other drugs.
Failure of
sulfa treatment (SMX/TMP or dapsone) was defined by occurrence of [greater than or equal to]1 of the following events within 5 days after PCP diagnosis: a change of drug treatment because of lack of clinical improvement, worsening of clinical features or gas exchange parameters, addition of corticosteroids, new need of mechanical ventilation, or death attributed to PCP.
These are the antibiotics that should be avoided if your child has a
sulfa allergy.
De acuerdo con los datos obtenidos en los analisis realizados a 20 cepas de Salmonella grupo D (moviles e inmoviles) aisladas en ponedoras comerciales, se pudo observar un comportamiento de resistencia muy variado que va desde el 0% para productos combinados como fosfomicina mas tilosina y trimetoprim
sulfa, hasta el 95% y 100% para productos de uso comun, como estreptomicina y tetraciclinas.
A randomized, double-blind trial was done to compare the effect of vitamin C on dyspareunia and vaginal discharge in women being treated with oral doxycycline and triple
sulfa vaginal cream for chamydial cervicitis.
The kits rely on ELISA--enzyme-linked immunosorbent assays--to detect trace amounts of sulfonamides, or "
sulfa drugs," in wastewater.
JACKSON, SOUTH CAROLINA: Patients who are allergic to
sulfa and require a diuretic ("water") pill have several options, In general, the
sulfa contained in antibiotic drugs has a slightly different chemical structure than the
sulfa corn pounds found in diuretics.
Sequence variation of the hydroxy methyldihydropterin pyrophosphokinase: dihydropteroate synthase gene in lines of the human malaria parasite, Plasmodium falciparum, with differing resistance to
sulfa. Eur J Biochem 1994; 224 : 397-405.