sulbactam


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Related to sulbactam: cefoperazone, Tazobactam

sulbactam

 [sul-bak´tam]
a β-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins and cephalosporins against β-lactamase–producing organisms.

sul·bac·tam

(sŭl-bak'tam),
A β-lactamase inhibitor with weak antibacterial action; when used in conjunction with penicillins (for example, ampicillin) with little β-lactamase-inhibiting action, it greatly increases their effectiveness against organisms that would ordinarily not be susceptible.

sulbactam

(sŭl-băk′tăm)
n.
A compound, C8H11NO5S, that inhibits action of the enzyme beta-lactamase, thus counteracting bacterial resistance to beta-lactam antibiotics. It is used in its sodium form in combination with antibiotics such as amoxicillin to treat infections caused by antibiotic-resistant bacteria.

sul·bac·tam

(sŭl-bak'tam)
A β-lactamase inhibitor with weak antibacterial action; when used in conjunction with penicillins with little β-lactamase-inhibiting action, greatly increases their effectiveness against organisms that would ordinarily not be susceptible.

sul·bac·tam

(sŭl-bak'tam)
A β-lactamase inhibitor with weak antibacterial action; when used with penicillins with little β-lactamase-inhibiting action, it greatly increases their effectiveness.
References in periodicals archive ?
Cefepime Tazobactam is more effective than Cefoperazone Sulbactam, Ceftazidime Sulbactam and Piperacillin Tazobactam.
In preclinical studies, ETX2514 restores sulbactam antibacterial activity against A.
To maintain the susceptibility of colistin, carbapenems, sulbactam, rifampicin and tigecycline have been the most studied, in order to find a combination that would provide the best clinical efficacy and reduce toxicity [27].
Antimicrobial susceptibilities of cefoperazone alone and in combination with sulbactam against GPCs are shown in [Table 2] and those against GNBs are shown in [Table 3].
To evaluating the efficacy of the drug combination as an option for therapy all the isolates were tested for the bactericidal synergistic effect by using sulbactam and tazobactam incorporated in agar with meropenem or colistin E-test strip (Biomeurix, France) on plate, Different sets of MHA plates incorporated with Sulbactam or tazobactam were prepared for respective combination depending upon the MICs of the organisms to be tested, For example the isolates with MIC of 8, 16, 32, 64, 128, 256, and 512 pg/mL were plated on MHA agar media plates incorporated with 4, 8, 16, 32, 64, 128, and 256 [micro]g/mL of sulbactam or tazobactam respectively followed by E-test strip,
baumannii incluyen carbapenemicos, aminoglucosidos (gentamicina o amikacina), sulbactam, colistina y tigeciclina (24).
The abscess treatment plan includes incising and draining the abscess, and treating the child with parenteral antibiotics, such as clindamycin or a combination of sulbactam and ampicillan.
The treatment plan for a retropharyngeal abscess includes incising and draining the abscess, and treating the child with parenteral antibiotics such as clindamycin or a combination of ampicillin and sulbactam.