sulbactam


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Related to sulbactam: cefoperazone, Tazobactam

sulbactam

 [sul-bak´tam]
a β-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins and cephalosporins against β-lactamase–producing organisms.

sul·bac·tam

(sŭl-bak'tam),
A β-lactamase inhibitor with weak antibacterial action; when used in conjunction with penicillins (for example, ampicillin) with little β-lactamase-inhibiting action, it greatly increases their effectiveness against organisms that would ordinarily not be susceptible.

sulbactam

/sul·bac·tam/ (sul-bak´tam) a β-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins and cephalosporins against β-lactamase–producing organisms.

sulbactam

(sŭl-băk′tăm)
n.
A compound, C8H11NO5S, that inhibits action of the enzyme beta-lactamase, thus counteracting bacterial resistance to beta-lactam antibiotics. It is used in its sodium form in combination with antibiotics such as amoxicillin to treat infections caused by antibiotic-resistant bacteria.

sul·bac·tam

(sŭl-bak'tam)
A β-lactamase inhibitor with weak antibacterial action; when used in conjunction with penicillins with little β-lactamase-inhibiting action, greatly increases their effectiveness against organisms that would ordinarily not be susceptible.

sul·bac·tam

(sŭl-bak'tam)
A β-lactamase inhibitor with weak antibacterial action; when used with penicillins with little β-lactamase-inhibiting action, it greatly increases their effectiveness.

sulbactam

an irreversible β-lactamase inhibitor which increases the activity of β-lactam antibiotics. Commonly used in combination with ampicillin and occasionally with cephalosporins.
References in periodicals archive ?
In preclinical studies, ETX2514 restores sulbactam antibacterial activity against A.
The combination of sulbactam and cefoperazone showed better activity against various GNBs tested compared to cefoperazone alone [Table 3].
Results showed high MIC value for sulbactam, tazobactam and meropenem with MIC [greater than or equal to] 16, MIC [greater than or equal to] 32 and MIC [greater than or equal to] 16 pg/mL respectively (Figure 1).
In group 2, administration of Amoxicillin + Sulbactam by intramuscular route caused 84.
baumannii incluyen carbapenemicos, aminoglucosidos (gentamicina o amikacina), sulbactam, colistina y tigeciclina (24).
Presenta mayor resistencia antibiotica a la ampicilina sulbactam (66,6%), acido nalidixico (33,3%) y ampicilina (16,6%).
In-vitro activity of cephalosporins alone and combined with sulbactam against various strains of Acinetobacter baumannii with different antibiotic resistance profiles.
The abscess treatment plan includes incising and draining the abscess, and treating the child with parenteral antibiotics, such as clindamycin or a combination of sulbactam and ampicillan.
The treatment plan for a retropharyngeal abscess includes incising and draining the abscess, and treating the child with parenteral antibiotics such as clindamycin or a combination of ampicillin and sulbactam.
Through hyperproduction, E coli can create exponentially large concentrations of the enzyme that render suicidal agents such as sulbactam ineffective.