sudden unexplained death in epilepsy

sudden unexplained death in epilepsy

A diagnosis which requires an autopsy for the death to be so labelled, which is defined as a “…sudden (in minutes to hours), unexpected (i.e., in his or her usual state of health during normal activities), witnessed or unwitnessed, non-traumatic and non-drowning death in a patient with known epilepsy, with or without evidence of seizure and excluding documented status epilepticus, in which post-mortem examination doesn’t reveal an anatomical or toxicologic cause of death.”

By definition, SUDEP is a diagnosis of exclusion and not due to any medical cause of death, respiratory disease (e.g., suffocation, asphyxia, aspiration, apnoea or respiratory failure), neurogenic pulmonary oedema, or cardiac disease (e.g., sympathetic (arrhythmias) or parasympathetic (bradycardia, asystole) activity). Post-mortem examinations in such patients is intended to exclude microscopic causes of death, e.g., myocardial fibrosis, pulmonary oedema, cerebral oedema.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
He said this gives hope that new therapies could be developed in the future to help prevent sudden unexplained death in epilepsy. But, he added, the current study was small and more research is needed to confirm the findings.
Pathologist Dr Maureen O'Sullivan gave cause of death as sudden unexplained death in epilepsy.
Coroners' autopsy reporting of sudden unexplained death in epilepsy (SUDEP) in the UK.
Senior Birmingham Coroner Louise Hunt recorded a narrative conclusion that Laura had died from sudden unexplained death in epilepsy combined with anorexia.
Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy. J Neurosci 2010; 30: 5167-5175, doi: 10.1523/JNEUROSCI.5591-09.2010.
Yn ystod yr wythnos hefyd, rhown sylw i sioe ddiweddaraf Bara Caws, Dros y Top, i 90ain Cynhadledd Sefydliad y Merched a gynhelir yn Wrecsam, a byddwn yn cloi'r wythnos yng Nghlwb Rygbi Bangor lle bydd noson arbennig i godi arian ac ymwybyddiaeth i elusen SUDEP - Sudden Unexplained Death in Epilepsy.
And during the trial medical experts will be asked to address the issue of whether Mr McNulty died as a result of the assault; as a result of his fall in the bathroom; or as a result of a sudep (sudden unexplained death in epilepsy) and if so whether that was related or unrelated to the ATTACK.
The 4-year-old boy died from what doctors believe was sudden unexplained death in epilepsy.
"Awareness about the condition is extremely important as sudden unexplained death in epilepsy accounts for 10% of all epilepsy related deaths,' said the neurologist.
It's long been debated whether to tell parents of the risk of sudden unexplained death in epilepsy
As noted by the Autism Tissue Program (ATP) more than a decade ago, sudden unexplained death in epilepsy (SUDEP) has been identified as a cause of death in individuals with autism."
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