Brugada syndrome

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Brugada syndrome

A family of autosomal dominant conditions which manifest themselves in young individuals—especially from southeast Asia—with no known heart problems or defects, who suffer sudden cardiac death or aborted sudden cardiac death.
 
EKG
Right bundle branch block; persistent ST-segment elevation in V1 to V3, unexplained by electrolyte disturbances; ischaemia; structural heart disease.
 
Management
Implantable defibrillator.

Brugada syndromes
Type—MIM Number—Defective gene    
Brugada-1—601144—SCN5A      
Brugada-2—611778—GPD1L-611778
Brugada-3—114205—CACNA1C-
Brugada-4—600003—CACNB2
Brugada-5—604433—KCNE3
Brugada-6—600235—SCN1B

Brugada syndrome

Cardiology A condition in which people with no known heart problems or defects suffer sudden cardiac death or aborted sudden cardiac death EKG Right bundle branch block, persistent ST-segment elevation in V1 to V3 unexplained by electrolyte disturbances, ischemia, structural heart disease Treatment Implantable defibrillator. See Long Q-T syndrome.

Brugada syndrome

(broo-gŏd′ă)
A rare hereditary syndrome, occasionally autosomal dominant, marked by right bundle branch block, S-T segment elevation in the right precordial leads of the ECG, and a high risk of sudden death from ventricular arrhythmias.
References in periodicals archive ?
Sian Regan, 29, who lost her brother Gareth Thomas to sudden death syndrome and is now a bereavement support worker
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An open letter, signed by both Labour and Liberal Democrat politicians, Liverpool mayor Joe Anderson and ECHO editor Alastair Machray, calls on Mr Hunt to meet with them to discuss the goals of the ECHO and Oliver King Foundation's campaign to stop more youngsters dying needlessly of Sudden Death Syndrome (SADS).
As well as 85 dying from abuse or neglect they came across up to 35 cases of children dying from sudden death syndrome, suicide and accidents.
Hypertrophic cardiomyopathy, which is incurable, is a genetic disease of the heart muscle where the muscle wall of your heart becomes thickened and is the biggest cause of sudden death syndrome in adults in the UK.
Hypertrophic cardiomyopathy, which is incurable, is an genetic disease of the heart muscle where the muscle wall of your heart becomes thickened and is the biggest cause of sudden death syndrome in adults in the UK.
An unexplained sudden death is frequently recorded as due to natural causes but experts now believe most of these deaths are due to sudden death syndrome.
He said Mrs Rodgers could have died from natural causes and the jury could not rule out unexplained sudden death syndrome.
This week we will be marking CRY Awareness Week and paying tribute to the many young people who die every year from sudden death syndrome.