succinyl-CoA


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suc·ci·nyl-co·en·zyme A

(sŭk'si-nil-kō-en'zīm),
The condensation product of succinic acid and CoA; one of the intermediates of the tricarboxylic acid cycle and a precursor in the synthesis of heme.

suc·ci·nyl-co·en·zyme A

(sŭk'si-nil-kō-en'zīm)
The condensation product of succinic acid and CoA; one of the intermediates of the tricarboxylic acid cycle and a precursor in the synthesis of heme.
Synonym(s): succinyl-CoA.

succinyl-CoA

a high energy intermediate metabolite formed in the Krebs cycle by the oxidation of α-ketoglutaric acid.
References in periodicals archive ?
MMA is caused by a defect in the conversion of L-methylmalonyl-CoA to succinyl-CoA, catalyzed by the enzyme methylmalonylCoA (MMCoA) mutase (EC.
Functional mut converts methylmalonic acid-CoA to succinyl-CoA.
2] Malate dehydrogenase 4 NADH 10 Malate dehydrogenase -4 NADH -10 Malate dehydrogenase 4 NADH 10 Gluconeogenesis Phosphoenolpyruvate -4 carboxykinase Phosphoglycerate kinase -4 Glyceraldehyde 3-phosphate -4 NADH -10 dehydrogenase Glycolysis Glyceraldehyde 3-phosphate 4 NADH 10 dehydrogenase Phosphoglycerate kinase 4 Pyruvate kinase 4 Decarboxylation Pyruvate dehydrogenase 4 NADH 10 of Pyruvate complex Krebs cycle Isocitrate dehydrogenase 4 NADH 10 [alpha]-ketoglutarate 4 NADH 10 dehydrogenase complex Succinyl-CoA synthetase 4 Succinate dehydrogenase 4 6 FAD[H.
Synthesis of methionine and succinyl-CoA depends on the coenzyme activity of cobalamin.
The 3-hydroxypropianate cycle is another unidirectional pathway in which acetyl-CoA is reductively transformed through carboxylation reactions into succinyl-CoA via the 3-hydroxypropianate intermediate.
These are further metabolized to yield acetyl-CoA, acetoacetate, and succinyl-CoA.
Succinyl-CoA and glycine through several steps requiring copper enzymes form d-aminolevulinic acid from which porphyrin is formed.
MMMconverts methylmalonyl-CoA to succinyl-CoA, an intermediate in the Krebs cycle.
12]) dependent enzyme, which converts L-methylmalonyl-CoA to succinyl-CoA.