succinimide


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suc·cin·i·mide

(suk-sin'ă-mīd),
Chemical class of drugs from which the antiepileptic agents ethosuximide, methsuximide, and phensuximide are derived. Unsubstituted succinimide has been used as an antiurolithic.
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Abbreviations DIC: N,N'-diisopropylcarbodiimide DIEA: N,N-diisopropylethylamine DMF: N,N-dimethylformamide EDC: 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide HOBt: 1-Hydroxybenzotriazole NHS: N-hydroxy succinimide PyBOP: Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate TFA: Trifluoroacetic acid THF: Tetrahydrofuran TIPS: Triisopropylsilane TMSCl: Trimethylsilyl chloride.
Different concentrations of succinimide were added to the reaction cell with keeping other parameters constant.
Deposit control agents in the combustion chamber are compounds with high temperature stability, mainly succinimide derivatives [3, 4].
The [H.sup.1] chemical shift scaling factor (0.44) during the evolution period was determined experimentally from the [H.sup.1] chemical shifts of [N.sup.15] enriched succinimide.
By the similar manner, the other succinimide esters (3b-d) were prepared as follows.
The first step is the activation of the MUA-carboxyl groups on the surface with a mixture of 0.1 M EDC and 0.1 M NHS to give reactive succinimide esters.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC), N-hydroxyl succinimide (NHS), and 2-(N-morpholino) ethanesulfonic acid were purchased from Shanghai covalent Chemical Technology Co., Ltd, Shanghai, China.
[17] constructed the adsorption isotherms of succinimide dispersants with different chain lengths and found the optimum chain length (acting as a lipophilic part) which gives higher adsorption and hence the better coverage of the surface which is a requirement of a stable dispersion.
Metal complexes of succinimide and phthalimide are of interest due to their unique structural features and potential pharmacological applications [10-11].
N-ethyl-N-(3-dimethyl aminopropyl) carbodiimide hydrochloride (EDC, 26mM) and 10 mM N-hydroxy succinimide (NHS) were dissolved in 0.1 M 2-(N-morpholino) ethane-sulfonic acid (MES) buffer (pH=8.3).