succinate dehydrogenase


Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.

suc·ci·nate de·hy·dro·gen·ase

a flavoenzyme that catalyzes the removal of hydrogen from succinic acid and converts it into fumaric acid; for example, succinate + FAD ⇄ fumarate + FADH2; this complex is a part of the tricarboxylic acid cycle.

succinate

any salt of succinic acid.

succinate dehydrogenase
an enzyme of the TCA cycle, located in the inner mitochondrial membrane that splits off hydrogen from succinic acid.
References in periodicals archive ?
However, Succinate dehydrogenase activity was recorded rich in the species of Rhodophyceae which shown the range of 0.
Activity of glycogen phosphorylase (GP) and the content of glycogen in cytosolic fraction and the activities of isocitrate dehydrogenase (ICDH) and succinate dehydrogenase (SDH) in mitochondria liver and skeletal muscle of experimental animals Parameters CON FRU GP (A): Liver 4.
A number of previous reports have examined the activity of succinate dehydrogenase in aging.
Medium and high activities of phenoloxidase and succinate dehydrogenase, respectively, were found in axial an radial parenchyma lumina towards vascular cambium.
Professor So Iwata of Imperial College London, who led the research, reported in the journal Science, ``Solving the structure of succinate dehydrogenase opens up new leads in the quest to understand longevity and ageing.
13] Recent studies have shown a germ line mutations in succinate dehydrogenase (SDH), leading to complete loss of SDH protein.
At the cellular level, 3NPA inhibits succinate dehydrogenase [4, 5], a key enzyme of oxidative energy production that is localized in the mitochondrial inner membrane and complex II of the respiratory chain, causing ATP levels in the brain to fall.
We used this enzymatic test, based on the cleavage of MTT into a blue-colored product (formazan) by mitochondrial enzyme succinate dehydrogenase (Mossman 1983), to evaluate JEG3 cell viability exposed to Roundup or glyphosate during various times.
These genes included succinate dehydrogenase (SDHC), cytochrome c oxidase (COX5B/ COX6B), and various genes of the ATP synthase complex (ATP5G1, ATP5C1, ATP5J, ATP5B, ATP5A1, ATP50, and ATP5F1).
2 translocation-associated renal cell carcinoma; p63, high-molecular-weight cytokeratin and racemase cocktail [PIN4]/phosphatase and tensin homolog [PTEN] for some cases of intraductal carcinoma of the prostate; and succinate dehydrogenase subunit B in renal cell carcinoma and pheochromocytoma), amyloidosis of the genitourinary tract, and workup of neoplastic needle core kidney biopsies.