In 1963, some authors reported that subthalamotomy successfully treats tremors at a rate which is similar to that of thalamotomy (10).
Subthalamotomy: It is a lesioning procedure performed in the STN for the treatment of cardinal symptoms, such as bradykinesia and rigidity, when there is insufficient response to medical therapy in PD (17).
(10.) Andy O, Jurko M, Sias F Subthalamotomy in treatment of parkinsonian tremor.
It has previously been shown that subthalamotomy including the region of the ZI can lead to clinical improvement in PD .
Gill, "Unilateral subthalamotomy in the treatment of parkinson's disease," Brain, vol.
Macias et al., "Cognitive and neuropsychiatric effects of subthalamotomy for Parkinson's disease," Parkinsonism and Related Disorders, vol.
Yen, "Bilateral subthalamotomy for advanced Parkinson disease," Surgical Neurology, vol.
Prospective randomized 1-year follow-up comparison of bilateral subthalamotomy versus bilateral subthalamic stimulation and the combination of both in Parkinson's disease patients: a pilot study.
Bilateral subthalamotomy in Parkinson's disease: initial and long-term response.
and pallidotomy are 3 lesion-producing surgeries that help reduce PD symptoms.
This minimizes medication-induced dyskinesia, which may interfere with intraoperative microelectrode recordings and with the assessment of clinical improvement during intraoperative stimulation including the subthalamotomy effect.
As the subthalamotomy effect wanes, which may take between I and 14 days, the patient's medication may require adjustment but care must be taken to neither under nor over medicate.