subthalamic nucleus

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Related to subthalamic nucleus: striatum, globus pallidus, caudate nucleus

sub·tha·lam·ic nu·cle·us

a circumscript nucleus, shaped like a biconvex lens, located in the ventral part of the subthalamus on the dorsal surface of the peduncular part of the internal capsule immediately rostral to the substantia nigra. The nucleus receives a massive topographic projection from the lateral segment of the globus pallidus and a somatopically organized projection from the ipsilateral motor cortex; a smaller bundle of afferents from the centromedian nucleus of the thalamus terminates in the rostral part of the nucleus The subthalamic nucleus projects to both pallidal segments, to the pars reticulata of the substantia nigra, and in a small way to the ipsilateral pedunculopontine nucleus.
Farlex Partner Medical Dictionary © Farlex 2012

subthalamic nucleus

A basal ganglia nucleus that is found under the thalamus in the base of the diencephalon; it lies between the thalamus and the cerebral peduncle, just rostral to the substantia nigra. The subthalamic nucleus is a satellite of the globus pallidus with which it has reciprocal connections. Lesions of the subthalamic nucleus on one side of the brain produce hemiballismus.
See also: nucleus
Medical Dictionary, © 2009 Farlex and Partners


Jules B., French physician, 1828-1897.
centre médian de Luys - Synonym(s): centromedian nucleus
corpus luysi - Synonym(s): subthalamic nucleus
Luys body - Synonym(s): subthalamic nucleus
Luys body syndrome
nucleus of Luys - Synonym(s): subthalamic nucleus
Medical Eponyms © Farlex 2012
References in periodicals archive ?
The team started by using electrophysiology to measure the firing of electrical signals in nerve cells in the subthalamic nucleus of rats given a shock to their back paw.
Deep brain stimulation (DBS) either on the globus pallidus or the subthalamic nucleus resulted in improvement or abolishment of dystonia, both postural abnormalities and action dystonia (dystonia in voluntary movement).
Israel, "Microelectrode recording duration and spatial density constraints for automatic targeting of the subthalamic nucleus," Stereotactic and Functional Neurosurgery, vol.
Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease.
Coping and quality of life of patients with Parkinson disease who have undergone deep brain stimulation of the subthalamic nucleus. Surgical Neurology, 72(2), 105-110; discussion 110-101.
(5.) De la Casa-Fages B, Grandas F Dopamine dysregulation syndrome after deep brain stimulation of the subthalamic nucleus in Parkinson's disease.
The subthalamic nucleus in the context of movement disorders.
Clinical motor outcome of bilateral subthalamic nucleus deep-brain stimulation for Parkinson's disease using image-guided frameless stereotaxy.
In a clinical study published in the New England Journal of Medicine, a six-month study of patients younger than 75 with severe motor complications of PD demonstrated that neurostimulation of the subthalamic nucleus was more effective than medical management alone.
nucleus accumbens, subthalamic nucleus and lower thalamic peduncle.