substrate specificity

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Related to substrate specificity: Lock and Key Model, Lock and Key Theory

sub·strate spec·i·fic·i·ty

the ability of an enzyme to recognize and bind its substrates, typically measured by the Vmax/Km or kcat/Km ratios.
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References in periodicals archive ?
The substrate specificity of neutral amino acid transport systems in sea urchin larvae was investigated by measuring the inhibition of alanine transport in the presence of other neutral amino acids present in molar excess.
Thus the enzyme showed broad substrate specificity and it hydrolyzed aryl phosphates much more efficiently than the aliphatic phosphates.
To assess the substrate specificity of a-1,6-ManTase of the C.
The enzyme exhibited broad range substrate specificity. p-NPP, phenyl phosphate, a-and b-naphthyl phosphate and b-glycero phosphate were found good substrates.
Besides, porcine GLUT2 conserves other motifs that may be critical for either transport activity or substrate specificity (Zhao, 2007): PESPRY/FLL in loop 6, GRR in loop 8, PMY in TM4,GPGPIP/TW in TM 10, and PETKG in the C-terminal tail.
The substrate specificity of TK2 is different from that of TK1, e.g., thymidine analogs such as AZT are phosphorylated at much lower efficiency by TK2 than by TK1 (4, 5), a feature that is of particular importance for the assay described here.
There are several isoforms of carboxylesterases that have been classified based on substrate specificity and their isoelectric point (26).
The substrate specificity of the cellulase encoded by cel1A and xylanase encoded by xyn1B were investigated by incubating the enzymes with various substrates (Table I).
Matrilysin (MMP7) is a protease with broad substrate specificity, being able to degrade elastin, proteoglycans, fibronectin, and type IV collagen.