substrate specificity

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Related to substrate specificity: Lock and Key Model, Lock and Key Theory

sub·strate spec·i·fic·i·ty

the ability of an enzyme to recognize and bind its substrates, typically measured by the V_max/K_m or k_cat/K_m ratios.

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1) Examination of the substrate specificity of hyaluronidase SD.

Synthesis of neoproteoglycans using the transglycosylation reaction as a reverse reaction of endo-glycosidases

The substrate specificity of neutral amino acid transport systems in sea urchin larvae was investigated by measuring the inhibition of alanine transport in the presence of other neutral amino acids present in molar excess.

Nutrient uptake by marine invertebrates: cloning and functional analysis of amino acid transporter genes in developing sea urchins (Strongylocentrotus purpuratus)

Thus the enzyme showed broad substrate specificity and it hydrolyzed aryl phosphates much more efficiently than the aliphatic phosphates.

Isolation, Purification and Characterization of Acid Phosphatase from Germinating Vigna radiata Seeds

To assess the substrate specificity of a-1,6-ManTase of the C.

Immunochemistry of pathogenic yeast, Candida species, focusing on mannan

The enzyme exhibited broad range substrate specificity. p-NPP, phenyl phosphate, a-and b-naphthyl phosphate and b-glycero phosphate were found good substrates.

Purification and Biochemical Properties of Acid Phosphatase from Rohu Fish Liver

Besides, porcine GLUT2 conserves other motifs that may be critical for either transport activity or substrate specificity (Zhao, 2007): PESPRY/FLL in loop 6, GRR in loop 8, PMY in TM4,GPGPIP/TW in TM 10, and PETKG in the C-terminal tail.

Cloning and distribution of facilitative glucose transporter 2 (SLC2A2) in pigs

The substrate specificity of TK2 is different from that of TK1, e.g., thymidine analogs such as AZT are phosphorylated at much lower efficiency by TK2 than by TK1 (4, 5), a feature that is of particular importance for the assay described here.

Sensitive nonradiometric method for determining thymidine kinase I activity

There are several isoforms of carboxylesterases that have been classified based on substrate specificity and their isoelectric point (26).

Comparative Metabolism of Chloroacetamide Herbicides and Selected Metabolites in Human and Rat Liver Microsomes

The substrate specificity of the cellulase encoded by cel1A and xylanase encoded by xyn1B were investigated by incubating the enzymes with various substrates (Table I).

Cloning and Characterization of Cellulase and Xylanase Coding Genes from Anaerobic Fungus Neocallimastix sp. GMLF1

Matrilysin (MMP7) is a protease with broad substrate specificity, being able to degrade elastin, proteoglycans, fibronectin, and type IV collagen.

Colorectal carcinoma susceptibility and metastases are associated with matrix metalloproteinase-7 promoter polymorphisms