We found that the apparent half-lives of deca- to hepta-BDEs in serum increased with decreasing number of bromine substituents
However, it remains to be established whether or not the glucoside substituent
, which is common among the four compounds, is necessary for the interaction with the PDZ2.
This paper examines the effects of phenolic and methoxyl substituents
at the 6- and 7- positions of the 1,2,3,4-tetrahydroisoquinoline molecule on HPLC resolution of the above stereoisomers.
The researchers "train" the network by plugging chemical information on 32 first substituents
into the input layer.
With unparalleled depth and completeness, the coverage ranges from those compounds containing only a few fluorinated substituents
, typically employed in pharmaceutical and agricultural applications, to more heavily fluorinated compounds.
It is interesting to compare the catalytic activity of complex 3b with those of half-sandwich amido fluorenyl zirconium complexes bearing N-alkyl substituents
In the current study, clusters C24H12 and C54H18 are used to model a graphene layer, and a variety of benzene derivatives and electron-donor/acceptor molecules such as tetracyanoethylene (TCNE), tetracyanoquino-dimethane (TCNQ), 2,4,7-trinitrofluorenone (TNF), tetrathiafulvalene (TTF), and N,N-dimethyl para-phenyienediamine (DMPD) are chosen to get the effect of substituent
on the noncovalent interaction between graphene layer and aromatic molecules.
A pharmacophore begins with a three-dimensional map of the substituents
of a bioactive molecule that contribute to it being bioactive.
VP Si 363 is characterized by a free mercapto group on the rubber-active site and a combination of ethoxy groups and polymeric, amphiphilic substituents
on the silica-active site.
Secondary coding via introduction of direct codes (DC) for arbitrary substituents
(discrete parts of the molecules) is introduced.
The estrogenicity of bisphenol A-related diphenylalkanes with various substituents
at the central carbon and the hydroxy groups.
Effects of aromatic substituents
on the photocleavage of 1-acyl-7-nitroindolines.