substantivity


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substantivity

(sŭb-stan-tiv'i-tē),
Term comprising the adherent qualities of a sunscreen and its ability to be retained after the skin is exposed to water and perspiration. Persistence of effect of a topically applied drug or cosmetic, determined by the degree of physical and chemical bonding to the surface; resistance to removal or inactivation by sweating, swimming, bathing, and friction, among other factors.

substantivity

[-stəntiv′itē]
the property of continuing therapeutic action despite removal of the vehicle, such as the action of certain shampoos.

sub·stan·tiv·i·ty

(sŭb'stăn-tiv'i-tē)
1. Property of continuing therapeutic action despite removal of vehicle.
2. The ability of an antimicrobial agent to retain its effectiveness in the mouth for an extended period.

sub·stan·tiv·i·ty

(sŭb'stăn-tiv'i-tē)
Term comprising adherent qualities of a sunscreen and its ability to be retained after the skin is exposed to water and perspiration.

substantivity,

adj pertaining to the capacity of an oral antimicrobial agent to continue its therapeutic activity for a prolonged period of time.
References in periodicals archive ?
The diverse bis anilines used as bridging component for compounds, did not affect the I>>max but increased the substantivity of dye with fiber (scheme-1).
Comparative evaluation of antibacterial property and substantivity of chlorhexidine containing dentifrices with sodium lauryl sulfate and Tween as surfactants: an in vivo study.
Chlorhexidine substantivity on salivary flora and plaque-like biofilm: an in situ model.
Chlorhexidine (2%) has been advocated as a final rinse irrigant owing to its substantivity, which allows binding to dentin and sustained antimicrobial activity, especially in endodontic retreatment.
31 In a study Harpreetsingh et al, substantivity of different concentrations of chlorhexidine in human dentin was evaluated.
It has a special property: substantivity, which enables long-lasting association with a substrate, prolonging its antimicrobial effect.
Even a staunch defender of the substantivity of metaphysics should accept that it is in principle possible, on some occasion, that we debate into a stalemate wherein we have two equally good descriptions of the structure of reality.
It is a skilled knowledge that keeps opening, prescriptivity, methodological pluralism, objectual correspondence conditions, typical of the methodology of research and it is adjusted to the principles of objectivity, objectual complexity, functional autonomy, methodological complementarity and significance, defended for the pedagogical research, on pain of not tackling the suitable substantivity of the educational action in Pedagogy.
Amongst the various chemical agents, chlorhexidine gluconate (CHX), a cationic bisguanide, has a broad spectrum antibacterial effect by virtue of its high intraoral substantivity and bactericidal and bacteriostatic activity.
This action can be attributed to its substantivity combined with its specificity against oral pathogens, thus being one of the most frequently prescribed topical antimicrobials in dentistry (Kidd 1991; Law and Seow 2007).
Triclosan is an antimicrobial ingredient; the added copolymer increases its substantivity to up to 12 hours.