subpotency

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subpotency

(sŭb-pōt′n-sē)
n.
Reduction in potency, as of a drug.

sub·po′tent adj.
References in periodicals archive ?
The inventor and earlier developers of laetrile unambiguously warned the NCI of what it already knew: racemic laetrile was subpotent. Yet, knowing that, NCI deliberately tested this racemic version of laetrile and almost bragged about it in the final paper.
These imports are a health and safety risk to American consumers because they may have become subpotent or adulterated during foreign handling and shipping.
against counterfeit, diverted, subpotent, standard, adulterated,
(24) These counterfeit drugs may contain inactive ingredients, subpotent, or superpotent drugs that could cause unexpected side effects.
Examples of such hazards include drugs that are expired, subpotent, contaminated, counterfeit, improperly packaged or contain an incorrect dose.
If the current legislation were approved, a frightening and unintended result could be the import of expired, subpotent, contaminated, or counterfeit drugs--not to mention wrong or contraindicated product, incorrect doses, or medication unaccompanied by adequate directions for use.
"The drugs could also be counterfeit, contaminated or subpotent, among other things."
Of the 10 failed samples, 9 were significantly subpotent and 1 contained unacceptable levels of endotoxin, he said at the meeting.
Those bottles of the product, which is used for pediatric sedation, may contain a crystalline precipitate of an insoluble complex of midazolam and saccharin, which could lead to a subpotent dose.
He notes that of the 12 FDA recalls of defective supplements in 1989, one involved a number of subpotent products made by pharmaceutical giant Eli Lilly.
Moreover, the FDAAA required the FDA to develop "standards and identify and validate effective technologies for the purpose of securing the drug supply chain against counterfeit, diverted, subpotent, substandard, adulterated, misbranded or expired drugs." There was no deadline set for the FDA to accomplish this, and the agency has not made much progress.
"These outlets may dispense expired, subpotent, contaminated or counterfeit products; the wrong or a contraindicated product; an incorrect dose; or medication unaccompanied by adequate directions for use."