sublingual testosterone

sublingual testosterone

Androtest-SL® Urology A format for delivering physiologic testosterone, where a molecule of testosterone forms an inclusion complex with hydroxypropyl-β-cyclodextrin. See Infertility.
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(10) However, within 3 to 4.5 hours after reaching peak testosterone levels, women reported a statistically significant increase in genital responsiveness, along with significant increases in genital arousal and subjective reports of "genital sensations" and "sexual lust." Administration of sublingual testosterone (0.5 mg) increases the sensitivity of the brain to sexual cues, regardless of circulating plasma levels of testosterone.
Sublingual testosterone forms are less efficient and need to be taken twice a day.
Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study.
Pharmacokinetics, bioefficacy, and safety of sublingual testosterone cyclodextrin in hypogonadal men: comparison to testosterone enanthate--a clinical research center study.
Also under study are sublingual testosterone cyclodextrin and buccal testosterone, which deliver high-peak serum testosterone levels.
(30) Using this as a guideline, physiologic doses of 7 to 10 mg/day of topical or sublingual testosterone are typically sufficient to affect metabolic processes in males with measured low or suboptimal levels.