sublingual immunotherapy


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sublingual immunotherapy

Abbreviation: SLIT
Allergen desensitization in which the antigen is administered in droplet form under the tongue instead of being injected subcutaneously. SLIT is a relatively safe form of immunotherapy and is often used at home instead of in a medical office, several times a week.

Patient care

Adverse effects include oral itching or swelling and gastrointestinal upset. The incidence of systemic side effects may be reduced with SLIT as opposed to immunotherapy by subcutaneous injection.

See also: immunotherapy
References in periodicals archive ?
Anaphylaxis to multiple pollen allergen sublingual immunotherapy.
A prospective, randomized, double-blind, placebo-controlled multi-centre study on the efficacy and safety of sublingual immunotherapy (SLIT) in children with seasonal allergic rhinoconjunctivitis to grass pollen.
Grading local side effects of sublingual immunotherapy for respiratory allergy: Speaking the same language.
Sublingual immunotherapy for allergic rhinitis: systematic review and meta-analysis.
Saporta D, McDaniel AB Safety and efficacy comparison of multiple-antigen subcutaneous immunotherapy with multiple-antigen sublingual immunotherapy.
But over a 3-year study period, the investigators observed a significant reduction in nasal obstruction, itching and cough, and a decreased need for symptom-relief medications in patients treated with standard medications plus sublingual immunotherapy, compared with those treated only with for allergic rhinitis and asthma.
Obviously, these results will lead the clinical development program for Actair(R), our sublingual immunotherapy tablet for the treatment of allergic rhinitis triggered by dust mites, to also focus on the treatment of asthma in patients allergic to mites", adds Albert Saporta, Chairman and CEO of Stallergenes.
Our trials were designed to evaluate a safe dosing regimen for sublingual immunotherapy, which is what the U.
A pioneer and leader in sublingual immunotherapy treatments, Stallergenes devotes over 20% of its turnover, in gross terms, to Research and Development and is actively involved in the development of a new therapeutic class: sublingual immunotherapy tablets.
Rotskoff is a Chicago allergist on the forefront of sublingual immunotherapy (SLIT) allergy drops for childhood nasal allergies and allergic rhinitis (hay fever).
In the two active arms, there was no dose escalation and the daily dose was a 300 IR sublingual immunotherapy tablet.