Linear IgA dermatosis is a rare autoimmune subepidermal
bullous disease that is rarely encountered by the otolaryngologist.
blister formation in the course of severe SLE occurs due to extensive interface inflammation and basal cell vacuolation, showing polycyclic erosions with an advancing blistering border predominantly on sun-exposed areas.
Keratinocyte apopytosis may involve all layers of the epidermis and lead to formation of bulla by affecting the subepidermal
region is parenchymatous (Figure 2D).
The primary parietal cells divided repeatedly through periclinal and anticlinal divisions to form the subepidermal
endothecium and two middle layers (Fig.
57,58) Histopathology is non-specific and shows spongiosis, occasional subepidermal
split and eosinophilic infiltration.
The external wall presents exoskeleton elements constituted by beams and rafters forming a subepidermal
network covered by a fine epidermis, which in contrast with other contemporaneous genera like Pseudocyclammina Yabe and Hanzawa, prolong to the septa (structured septa in Hottinger, 1967).
Sections showing scattered nonspecific lyphohistiocytic infiltration with cellular reaction within dermal nerve or presence of bacilli in subepidermal
zone/arrector pilorum muscle/dermal nerve were classified as indeterminate leprosy.
The "first smother, then pull" approach does not always work with botfly larvae because they have spines on their bodies that can hook into subepidermal
moisture is associated with early pressure ulcer damage in nursing home residents with dark skin tones.
They comprised such characteristic features as lymphohistiocytic bandlike infiltrate occupying the upper dermis and obscuring the dermoepidermal junction, irregular acanthosis resembling the typical saw-toothed appearance, extensive liquefactive degeneration of the basal layer of the epidermis with subepidermal
clefts (Max Joseph spaces), pigmentary incontinence, and numerous cytoid bodies forming huge clusters.
Skin biopsy from the bullous lesions revealed multiple subepidermal
bullae with ill defined macrophage-filled granulomas and a dense neutrophilic infiltrate (Figure 4).