28], These cytokines play key roles in regulating vessel wall tone by affecting the release of nitric oxide and endothelin-1 in the subendothelial space
In normotensive rats,  LDL cholesterol ingresses into subendothelial space
causing further oxidative damage and imbalance the ability of macrophages to scavenge the lipoproteins are saturated.
Penetration of modified LDL into the subendothelial space
in areas with increased endothelial permeability leads to the formation of focal lipid infiltrations into the intima.
Chronic endothelial injury and dysfunction resulting from the presence of atherosclerosis, and the inflammatory and metaplastic changes that it induces in the vascular subendothelial space
, are central to our present understanding of vascular and atherosclerotic pathogenesis.
The vasculitis involves destruction of small to medium-sized arteries that contain an inflammatory infiltrate within the vessel wall and subendothelial space
, leading to destruction of the elastic lamina (figure 1).
2003) and in late embryonic period liver become enlarged and considerable functional or morphological development of chick liver such as formation of subendothelial space
were occurred at late incubation specially after day-16 (SandstrOm and Westman, 1971; Suksaweang et al.
LDLOx is internalized and accumulates in macrophages, turning them into foam cells that remain in subendothelial space
Oxidized low-density lipoprotein (LDL) within the subendothelial space
is converted by Lp-PLA2 into oxidized free fatty acids and lysophoshatidylcholine (Macphee et al.
The vWF is discharged by endothelial cells inside a blood-flow (supporting concentration in plasma), and aside in subendothelial space
, where it joins with a structure of extracellular matrix.
LDL particle circulates in plasma, including a fraction, which reenters the circulation from the subendothelial space
As atherogenic lipoproteins such as very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) infiltrate the subendothelial space
, they can be oxidized by such enzymes as myeloperoxidase, 5'-lipoxygenase, and
When low-density lipoprotein (LDL) cholesterol infiltrates the subendothelial space
and becomes oxidised, a complex inflammatory process is triggered.