Acute GLYX-13 (rapastinel) ameliorates acute ketamine and subchronic
ketamine-and phencyclidine-induced memory deficits in C57BL/6J mice.
toxicity and mutagenic study revealed that CQhas no adverse effects at therapeutic doses and can be considered as safe for long-term treatment (Shil et al.
Interestingly, medical case reports dating back to the early 1900s have documented the appearance of fine punctate irritating rashes, herpetic skin eruptions, and HZ in people shortly after they recovered from acute and subchronic
arsenic poisoning (Bartolome et al.
Subject of the contract is to be awarded a framework agreement for the production, delivery and analysis of specified food for 3 toxicological studies (combined KarzinogenitEnt- / chronic toxicity study, 2 subchronic
studies) in rats.
toxicity study of water pepper extract in F344 rats.
Acute and subchronic
toxicity of thymoquinone in mice.
With the recent completion of additional subchronic
non-clinical toxicology work, ZPL-389 is ready for patient studies which are the subject of the TSB grant.
Psychosocial predictors of outcome in acute and subchronic
low back trouble.
The modulatory effects of ellagic acid and vitamin E succinate on TCDD induced oxidative stress in different brain regions of rats after subchronic
feeding study of grain from herbicide-tolerant maize DP-098140-6 in Sprague-Dawley rats.
Experiment 1: subchronic
ethanol consumption and survival analysis
The ensuing health effects chapter provides an extensive evaluation and interpretation of health effects, both human and animal, presented according to specific route (oral and inhalation) and duration (acute, subchronic
, and chronic) of exposure, and identifies levels of significant exposure in terms of no-observed-adverse effect levels (NOAELs) and lowest-observed-adverse effect levels (LOAELs).