subchondral

sub·chon·dral

(sŭb-kon'drăl),

Beneath or below the cartilages of the ribs.

subchondral

(sŭb″kŏn′drăl) [″ + Gr. chondros, cartilage]

Below or under a cartilage.

References in periodicals archive ?

Osteoarthritis (OA) is a progressive degenerative disease of the synovial joints in which the articular cartilage and the adjacent subchondral bone show the most noticeable changes.

Analytical Study of Clinicopathological Data of Saudi Patients with Osteoarthritis Subjected to Total Knee Arthroplasty/Estudio Analitico de Datos Clinico-Patologicos de Pacientes Sauditas con Osteoartritis Sometidos a Artroplastia Total de Rodilla

Other symptoms include narrowing of the joint space, synovial membrane thickening, osteophyte formation and increased density of subchondral bone.

Ampio Pharmaceuticals Updates Progress of SPA Clinical Trial

The poor self-hearing capacity of the cartilage has prompted strategies to repair damaged articulating surfaces with surgically-implantable, engineered osteochondral constructs that provide a fill thickness repair that seamlessly fuses with the subchondral bone.

Hypoxia inducible factor regulating scaffolds for osteochondral regeneration

Importantly, there were no indications of chondrolysis, osteonecrosis, subchondral insufficiency fractures, or clinically significant subchondral bone changes in any subgroup.

Flexion presents new data evaluating repeat administration of ZILRETTA

Bone loss develops as the unstable bony surfaces continue to rub roughly and unevenly, leading to joint space narrowing, exposure of the underlying subchondral bone, and precipitation of a process of bone remodeling in which the subchondral bone thickens.

Stem Cell Therapy as a New Paradigm in Osteoarthritis Treatment

The most common cause of non-traumatic bone fractures is avascular bone necrosis (AVN); the terms ischemic necrosis, osteochondritis dissecans, subchondral avascular necrosis are also used (6).

The Adverse Effects of High-dose Corticosteroids with Early and Late Severe Morbidity in the Treatment of Patients with Multiple Sclerosis: Long-term Observation Results/Multipl Skleroz Hastalarinin Atak Tedavisinde Yuksek Doz Kortikosteroid Kullaniminin Erken ve Gec Donem Agir Morbiditeye Yol Acan Yan Etkileri: Uzun Donem Gozlem Sonuclari

The presence of synovitis, capsulitis, and enthesitis or structural changes, in the context of erosions, subchondral sclerosis, periarticular fat deposition and ankylosis are suggestive of and are not sufficient alone to make the diagnosis of axial spondyloarthropathy (9).

Spectrum of skeletal disorders during the peripartum period: MRI patterns

Joint safety was a composite measure consisting of adjudicated outcomes of rapidly progressive osteoarthritis (RPOA) type 1 or type 2, subchondral insufficiency fracture, osteonecrosis or pathological fracture.

Eli Lilly & Company (NYSE: LLY) - Pfizer and Lilly Announce Top-Line Results From Long-Term Phase 3 Study of Tanezumab in Patients With Osteoarthritis -- 18/4/2019

Joint safety was a composite measure consisting of adjudicated outcomes of rapidly progressive osteoarthritis type 1 or type 2, subchondral insufficiency fracture, osteonecrosis or pathological fracture.

Pfizer and Lilly Release Top-Line Results from Long-Term Phase 3 Study of Tanezumab in Patients with Osteoarthritis

Additional findings on MR include decreased or absent enhancement, low T1 signal of the subchondral bone, and thickening of the cartilage overlying the flattened femoral head.

Musculoskeletal imaging in children: What the general radiologist should know

Spontaneous osteonecrosis of the knee (SONK) was first reported in 1968 by Ahlback.[1] It was defined as a distinct clinical entity with characteristic findings including a subchondral lesion in the weight-bearing region of a single condyle.

Clinical Characteristics and Treatment of Spontaneous Osteonecrosis of Medial Tibial Plateau: A Retrospective Case Study

When the disease reaches the subchondral region, there is separation in the articular cartilage, resulting in cartilage and bone erosion, destruction, and effusion.