Shen, "Predicting eukaryotic protein subcellular
location by fusing optimized evidence-theoretic K-nearest neighbor classifiers," Journal of Proteome Research, vol.
Based on the above results, pGH internalization peaked at 60 min; thus, in the following experiment, porcine hepatocytes were stimulated with pGH (100ng/mL) for 60min, followed by an anti-pGH antibody; a 12nm Gold-conjugated second antibody was used to observe pGH subcellular
localization by immunoelectron microscopy.
Summary: TEHRAN (FNA)- Merging lattice light sheet microscopy with adaptive optics reveals the most detailed picture yet of subcellular
dynamics in multicellular organisms.
This work focuses, in particular, on the morphologic events caused by venom activity at subcellular
In his review of Pharmacracy ("Head Games," January), Jacob Sullum quotes Thomas Szasz: "Attributing mental illnesses...to biological alterations occurring at a 'subcellular
level' is a parody of the denial of free will, choice, and responsibility."
He has been responsible for developing a number of widely used bioinformatics tools for the prediction of protein subcellular
localization such as PREDICTNLS, LOCKEY, LOCHOM, and LOC3D.
The virus-induced modifications at the cell surface or subcellular
surface could relate to the eventual destruction of the infected cells as well as shed light on the extrusion mechanism of the progeny virus particles from the cell surface.
In the July 2004 Ecology, Brown, West, and their colleagues proposed that their equation can shed light not just on individual animals' life processes but on every biological scale, from subcellular
molecules to global ecosystems.
A better understanding of subcellular
microorganism chemistry, specifically sporulation, might also help authorities neutralize bioterrorism threats before they become a problem.
distribution of metals within the kidney of the bivalve Mercenaria mercenaria (L.).
The LAMP sequence causes an antigen, to which it is attached, to be taken up by the lysosomal subcellular
compartment of the cell, an action that has been shown to increase presentation on MHC class II molecules, which in turn, can produce greater CD4+ T-cell responses against the antigen and a more potent and longer lasting overall immune response.
"This is the first nanotube-based sensor that can detect analytes at the subcellular
level," said Michael Strano, a professor of chemical and biomolecular engineering at the University of Illinois.