Haemorrage: Epidemiology, risk factors and treatment options.
Global and domain-specific cognitive impairment and outcome after subarachnoid
In recent years interventional cerebral procedures have received a lot of encouragement, especially after the international subarachnoid
aneurysm trial reported that endovascular management of acutely ruptured aneurysms may be superior to surgery.3 The trial reported a variable overall complication rate ranging between 0.6 and 10% in patients with cerebrovascular disease undergoing angiographies.
Recently, we successfully stimulated tight junction and adherens junction proteins by activating Frizzled-4 receptor, a canonical Wnt signaling receptor that is also expressed on pericytes , suggesting that pericytes may be a promising target to maintain blood-brain barrier integrity and functions during subarachnoid
hemorrhage treatment .
Sivilotti et al., "Sensitivity of computed tomography performed within six hours of onset of headache for diagnosis of subarachnoid
haemorrhage: Prospective cohort study," BMJ (Online), vol.
We provided first preclinical evidence that baicalin protected against subarachnoid
hemorrhagic brain injury.
Chen, "Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid
hemorrhage," Neuroscience, vol.
Evgen Pharma is a clinical stage drug development company whose lead programmes are in breast cancer and subarachnoid
haemorrhage, a type of stroke.
Does Neuroprotection Still Have a Role in Injured Brain Following Aneurysmal Subarachnoid
Pre-load all patients with 10 ml/kg Ringer lactate solution prior to subarachnoid
hemorrhages are very important owing to their high mortality and morbidity, although they are not frequent causes of urgent hospital admissions.
hemorrhage (aSAH) is often associated with poor functional and cognitive outcomes, (1) which are attributed to the initial hemorrhage, as well as secondary complications such as cerebral vasospasm, delayed cerebral ischemia, or myocardial injury.