stubborn

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stubborn

Vox populi → medtalk Refractory; unresponsive to therapy
References in periodicals archive ?
The lack of this basis--the thing we call "poverty"--is overwhelmingly, in the whole human world, the commonest, the grimmest, the stubbornest obstacle we know to the pursuit of happiness.
Fallon had to be at his stubbornest on Edinburgh owner Kevin Doyle's Ormelie.
Others found him frigid, crusty, aristocratic, intransigent (Mark Hanna, the Ohio Republican Party boss, called him the stubbornest man he had ever met), narrow-minded, conspiratorial, and (according to President Charles W.