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a very poisonous alkaloid from seeds of Strychnos nux-vomica and other species of Strychnos; a common strychnine-containing rodenticide causes convulsions in humans.
An alkaloid from Strychnos nux-vomica; colorless crystals of intensely bitter taste, nearly insoluble in water. It stimulates all parts of the CNS, and was used as a stomachic, an antidote for depressant poisons, and in the treatment of myocarditis. Strychnine blocks the inhibitory neurotransmitter glycine, and thus can cause convulsions. The formerly used salts of strychnine are strychnine hydrochloride, strychnine phosphate, and strychnine sulfate. It is a potent chemical capable of producing acute or chronic poisoning of humans or animals.
strychnine(strĭk′nīn′, -nĭn, -nēn′)
An extremely poisonous white crystalline alkaloid, C21H22O2N2, derived from nux vomica and related plants, used as a poison for rodents and other pests and formerly as a stimulant.
strychnineToxicology A highly toxic alkaloid from Strychnos nux-vomica, commonly used as a rodenticide, that elicits CNS hyperactivity, causing painful, recurrent tonic seizures, muscle tightness, cramping, risus sardonicus, marked flaccidity, decorticate posturing and death; Sx appear at 15 mg, death occurs with doses > 60 mg Management Control seizures with diazepam and phenobarbital; for muscle relaxation, curare, succinylcholine
An alkaloid from Strychnos nux-vomica; colorless crystals of intensely bitter taste, nearly insoluble in water; stimulates all parts of the central nervous system; was formerly used in stomach therapy, as an antidote for depressant poisons, and in the treatment of myocarditis. It blocks glycine, an inhibitory neurotransmitter, and thus can cause convulsions. It is a potent chemical capable of producing acute or chronic poisoning.