strontium ranelate

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strontium ranelate

A bone-seeking drug shown in the mid-1990s to be capable of substantially reducing the risk of fractures in post-menopausal women with OSTEOPOROSIS. The drug stimulates bone formation and reduces resorption. The usefulness of the drug was shown in a large trial, the results of which were published in January 2004. Side effects are said to be minor.

Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

References in periodicals archive ?

Strontium ranelate (SR), which has been demonstrated as an effective anti-osteoporosis remedy, has the potential to reduce the incidence of spinal and hip fracture in postmenopausal women (20).

Strontium ranelate inhibits wear particle-induced aseptic loosening in mice

In several double-blind trials, treatment with strontium in doses of 170-680 mg per day (as strontium ranelate) for two to five years significantly increased bone mineral density of the hip and spine and significantly reduced the incidence of fractures by 16-49%, compared with placebo, in postmenopausal women with osteoporosis.

Should We Stop Using High-Dose Strontium for Osteoporosis?

Saltel, and P Jurdic, "Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro," Bone, vol.

Percutaneous Injection of Strontium Containing Hydroxyapatite versus Polymethacrylate Plus Short-Segment Pedicle Screw Fixation for Traumatic A2- and A3/AO-Type Fractures in Adults

The objective of this paper is the analysis of the effectiveness of pharmacological correction of experimental osteoporosis with a combination of rosuvastatin with L-norvaline compared with drugs strontium ranelate (Bivalos) and Calcium D3 Nycomed.

Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment

The objective of this study was to compare the Primary and Secondary stability of immediate implant placement with Alveolar Ridge Augmentation (ARA) and Strontium Ranelate (SR) as aids to enhance the stability using Resonance Frequency Analysis (RFA).

Effects of Strontium Ranelate on Alveolar Ridge Morphology Augmentation/ Efectos del Ranelato de Estroncio en el Aumento del Reborde Alveolar

Strontium ranelate has been proven to favor bone healing by both increasing new bone formation and reducing bone resorption [15-18].

The Incorporation of Strontium in a Sodium Alginate Coating on Titanium Surfaces for Improved Biological Properties

"The Europeans use strontium ranelate (Protelos), which is not approved here.

For strong bones, supplements are sometimes needed: calcium and vitamin D supplements must be tailored to your health needs

I had read the research on strontium ranelate and was told by a friend of mine, a PhD osteoporosis researcher, that he thought at the 680 mg of strontium ranelate that was being used in Europe, we would ultimately hear of associated side effects.

Ask Dr. Zand

The investigators performed an ancillary study of patients enrolled in the phase III, randomized Strontium Ranelate in Knee Osteoarthritis (SEKOIA) trial, in which assessments included hand x-rays and hand symptoms.

Hand osteoarthritis, cardiometabolic disease linked

Analgesics, calcium and vitamin D, and strontium ranelate were prescribed.

Cortical stress reaction in two patients on bisphosphonate therapy: case report

Strontium ranelate is a developed drug that has been shown to be effective in reducing the risk of vertebral and hip fractures in postmenopausal women with osteoporosis.

Torque removal test of strontium chloride coated commercially pure titanium implant compared with hydroxyapatite coating