3 Formerly these were synonymous as sporadic olivopontocerebellar atrophy (sOPCA), striatonigral
degeneration and Shy-Drager syndrome respectively.
Coordinated and spatial upregulation of arc in striatonigral
neurons correlates with L-dopa-induced behavioral sensitization in dyskinetic rats.
Thin section MR study of the basal ganglia in the differential diagnosis between striatonigral
degeneration and parkinson disease.
Matsushita, "The distribution and dynamic density of oligodendroglial cytoplasmic inclusions (GCIs) in multiple system atrophy: a correlation between the density of GCIs and the degree of involvement of striatonigral
and olivopontocerebellar systems," Acta Neuropathologica, vol.
parkinsonian type (MSA-P), characterized by striatonigral
degeneration and increased spasticity
The diagnosis for probable MSA was performed by a neurologist through magnetic resonance imaging and confirmed by the predominant striatonigral
degeneration in the absence of cerebellar dysfunction, presence of cardinal features including parkinsonism, and symptoms of autonomic failure (Quinn and Wenning, 1996).
It regulates the striatonigral
neurons via D1-dopamine receptors but regulates the striatopallidal neurons via D2-dopamine receptors .
Different responsiveness of striatonigral
and striatopallidal neurons to L-Dopa after a subchronic intermittent L-Dopa treatment.
Striatal D2 receptor status in patients with Parkinson's disease, striatonigral
degeneration, and progressive supranuclear palsy measured with 11C-raclopride and positron emission tomography.
It has been documented that DA from substantia nigra neurons excites striatonigral
neurons, while another neurotransmitter, acetylcholine (ACh) from striatal cholinergic neurons, opposing DA action, inhibits striatonigral
MSA was originally divided into Shy-Drager syndrome, striatonigral
degeneration, and olivopontocerebellar atrophy, but this distinction is no longer made.
degenerations, putaminal pigments and nosology.