Considering the fact that elevation of gastric acid pH enables growth of gram-negative bacteria in the stomach, which then can reach the pharynx and lungs by aspiration, the risk of HAP would be greater if we apply a drug against stress ulcers
, which raises gastric acid pH (8,32,33).
Keywords: Hospital acquired pneumonia, Proton pump inhibitors, Stress ulcer
They are also used for stress ulcer
prophylaxis (SUP) and as gastroprotective agents along with NSAIDs.
Stanley, "Update on stress ulcer
prophylaxis in critically ill patients," Critical Care Nurse, vol.
Also prolonged mechanical ventilation and coagulopathy has been shown to be associated with increased risk of stress ulcers
in spinal injuries (21).
During this time, all patients admitted to the burns unit with burn injury requiring fluid resuscitation (>15% total body surface area, [TBSA]) routinely received stress ulcer
prophylaxis with ranitidine 150 mg, twice daily, from admission to discharge.
We targeted disease management, process changes and the development of a nursing-focused approach to care, including daily multidisciplinary rounding, utilization of a "daily goals checklist," VTE and stress ulcer
prophylaxis, implementation of the "Surviving Sepsis Campaign," an improved critical care triage system, evidence-based infection control initiatives, glycemic control, P & P's written for patient safety and an electronic medical alert for non-critical care patients developing sepsis.
Misoprostel versus antacid titration for preventing stress Ulcers
in postoperative surgical ICU patients.
The necessity for vitamin A in the diet to prevent stress ulcers
has been noted by another researcher, M.S.
Also, patients suffering from burns, shock, head injuries, or cancer, or those who have undergone extensive surgery, may develop "stress ulcers
." Bleeding can occur from benign tumors or cancer, although these disorders do not usually cause massive bleeding.
Another important indication is for stress ulcers
prophylaxis in critically ill patients, Zollinger Ellison syndrome is a condition in which indefinite therapy is required, similarly PPIs are used in symptomatic and recurrent functional dyspepsia patients2.
Clinically, the hospital achieved near-perfect compliance with best-practice protocols to prevent gastric stress ulcers
, blood clots and minimization of time that patients spent on a ventilator.