I spent most of my career studying lower urinary tract disease in cats, and it turns out that the disease in many cases is a consequence of this chronic activation of the stress response system
One of the most valuable aspects of the stress response system
is its feedback loop; when the threat subsides, the parasympathetic system returns the body to homeostasis, and the effects are reversed.
Another pathway that also has been implicated in alcohol abuse, and particularly in the transition to alcohol dependence, involves two stress-response systems, the hypothalamic-pituitary-adrenal (HPA) axis and the extra-hypothalamic corticotropin-releasing factor (CRF) stress response system
, which mediate the interaction of psychosocial stress and early alcohol use.
When we are exposed to stress, large quantities of neurohormones are released into the blood stream and in a pregnant woman this can change the developing foetus' own stress response system
," Professor Dieter Wolke, Professor of Developmental Psychology at University of Warwick and Warwick Medical School, who led the study, said.
This has led to the theory that fibromyalgia is an abnormality of the stress response system
Emotions consist of behavioural, endocrine and autonomic responses which are generally maintained in balance by the stress response system
Prolonged stress creates tension, nervousness and leaves the body's stress response system
turned on long term.
Moreover, it releases beta-endorphins, which tone the stress response system
and induce peaceful, positive mood states, thereby reducing the need to use substances of abuse.
Development of the HPA axis and the stress response system
in young birds post-hatch is considered to be a delicate balance between benefiting from the ability to mount an acute stress response and limiting the damaging effects of glucocorticoids.
Since serotonin is part of the stress response system
, the investigators posited that a variation in those receptors might predict a depression response, he added.
Tau phosphorylation may represent a physiological and reversible process integral to the stress response system
In particular, the article considers evidence that the glucocorticoid-based stress response system
, as regulated by the hypothalamic-pituitary-adrenal (HPA) axis, plays a key role in the physiological and psychological responses to alcohol.