streptogramin


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streptogramin

(strĕp-tō-gram'in),
A synthetic protein that breaks down DNA, used to thin out the pulmonary secretions of patients with cystic fibrosis.

strep·to·gra·min

(strep'tō-gram'in)
A mixture of two structurally distinct compounds, type A and type B, which act at the level of inhibition of translation through binding to the bacterial ribosome; separately bacteriostatic but bactericidal in appropriate ratios. Antibiotics quinupristin and dalfopristin are both streptogramins.

streptogramin

(strĕp″tō-grăm′ĭn)
Any of a class of antibiotics effective against gram-positive bacteria that bind to the bacterial ribosome and inhibit protein synthesis. An example is the combination antibiotic quinupristin-dalfopristin.
References in periodicals archive ?
Tn5406, a New Staphylococcal Transposon Conferring Resistance to Streptogramin A and Related Compounds Including Dalfopristin.
cfr also confers resistance to phenicol compounds, lincosamide, oxazolidinone, pleuromutilin, and streptogramin A.
Tober, Specific Inhibition of 50S Ribosomal Subunit Formation in Staphylococcus aureus Cells by 16-Membered Macrolide, Lincosamide, and Streptogramin B Antibiotics.
This gene mediates resistance to not only linezolid but also to phenicols, lincosamides, pleuromutilins, and streptogramin A and macrolides3.
Pristinamycin is a streptogramin that is used to treat vancomycin-resistant Enterococcus faecium bacteremia and complicated skin infections due to MRSA [60].
Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics.
Assessing risks for a pre-emergent pathogen: Virginiamycin use and the emergence of streptogramin resistance in Enterococcus faecium.
Makrolid, ketolid, linkozamid (linkomisin, klindamisin gibi) ve streptogramin B gibi antibiyotikler stafilokokal ribozo-ma baglanip protein sentezini inhibisyonuna yol acar.
Examining 10-year trends for macrolide, lincosaminde, and streptogramin antibiotics showed large increases in Peru (0.
Aminoglycosides: amikacin, gentamicin, netilmicin and tobramycin, arbekacin (2000) for MRSA, streptogramin, quinapristine/dalfopris (1999) for VRE (E.
Dalfopristinquinupristin (RP 59500), a streptogramin antibiotic, is the first antibiotic approved for the treatment of patients with serious or life-threatening infections associated with vancomycin-resistant E.