At 17th wpi prion disease also induced significant microgliosis on pyramidal cell layer and stratum radiatum (two-tail /-tests for independent samples, p < 0.
Although we did not estimate microglial numbers in the stratum oriens, we found an increase in the number of microglial cells in CA1, especially in the stratum radiatum and stratum pyramidale in prion diseased animals.
First row corresponds to pyramidal cell layer (Pyr) and stratum radiatum (Rad).
18) A stainless steel bipolar stimulating electrode (FHC, Bowdoinham, ME, USA) was placed in stratum radiatum to stimulate the Schaffer collaterals.
TDE's effect on fEPSPs was recorded in the stratum radiatum of the CA1 hippocampus, in response to stimulation of Schaffer collaterals.
The electrical stimulation of the afferent fibers in the stratum radiatum at the intensities of 25-200 [micro]A, elicited a synchronous firing of the CA1 pyramidal cells (Fig.
Tetanic stimulation in stratum radiatum induced LTP in three groups at 25 [micro]A stimulus intensity (Fig.
We found that although eugenol depresses baseline synaptic transmission, it has no effect on the induction of LTP produced by tetanic stimulation of stratum radiatum.
To exclude the possibility that alterations in PSSD might be a consequence of changes in the volume of reference, we used a subset of the vibratome sections for volume estimation of the stratum radiatum of CA1, using the Cavalieri's principle (Gundersen and Jensen 1987).
n] is the measured area of CA1 stratum radiatum for each section.
00 HR/HR-B CCD camera system (Hamamatsu Photonics, Hamamatsu, Japan), from an area located between the upper and middle third of the CA1 stratum radiatum (300-500 [micro]m from the pyramidal cell layer; Leranth et al.
Camera Lucida reconstruction of the morphology of biocytin-filled cells indicated that these interneurons had axonal arbors that were located primarily in stratum lacunosum-moleculare and stratum radiatum