stratum corneum


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Related to stratum corneum: stratum granulosum, Stratum spinosum

stratum

 [stra´tum, strat´um] (L.)
a sheetlike mass of tissue; see also lamina and layer.
stratum basa´le the deepest layer of the epidermis, composed of a single layer of basophilic cells. Called also basal layer of epidermis.
stratum cor´neum the outer horny layer of the epidermis, consisting of cells that are dead and desquamating. Called also horny layer.
stratum germinati´vum
1. the stratum basalis and stratum spinosum considered together; called also malpighian layer.
2. the lower layer of the nail, from which the nail grows; called also germinative layer.
stratum granulo´sum the cell layer of the epidermis lying between the stratum lucidum and the stratum spinosum. Called also granular layer.
1. the deep layer of the cortex of the cerebellum.
2. the layer of follicle cells lining the theca of the vesicular ovarian follicle; called also granular layer.
stratum lu´cidum the clear translucent layer of the epidermis, just beneath the stratum corneum. Called also clear layer.
stratum spino´sum the layer of the epidermis between the stratum granulosum and stratum basalis, marked by the presence of prickle cells; called also spinous layer and prickle-cell layer.

stratum corneum

(kôr′nē-əm)
n. pl. strata cornea
The horny outer layer of the epidermis, consisting of several layers of flat, nonnucleated, dead or peeling cells.

stratum corneum

the horny, outermost layer of the skin, composed of dead flat cells converted to keratin that continually flakes away. The thickness of the layer is correlated with the normal wear of the area it covers. The stratum corneum is thick on the palms of the hands and the soles of the feet but relatively thin over most areas. Also called horny layer. Compare stratum basale, stratum granulosum, stratum lucidum, stratum spinosum. See also skin.

stratum corneum

cornified layer outermost, fully keratinized area of epidermis

stratum

pl. strata [L.] a sheetlike mass of tissue of fairly uniform thickness; distinct layers making up various tissues or organs, as of the skin, brain, retina.

stratum avasculosum
the avascular stratum in the margin of the iris.
stratum basale
the mitotically active, basal layer of the epidermis, consisting of columnar to cuboidal keratinocytes on a basement membrane.
stratum corneum
the outer horny layer of the epidermis, consisting of cells that are non-nucleated, keratinized and desquamating.
stratum germinativum
in the epidermis, located between the stratum basale and the stratum granulosum. Together with the basal layer, called the malpighian layer. Called also germinative layer.
stratum granulosum
1. the layer of cells between the stratum lucidum and the stratum spinosum of the skin, very thin and not always present. Called also the granular layer.
2. the deep layer of the cortex of the cerebellum.
3. the layer of follicle cells lining the theca of the vesicular ovarian follicle. Called also granular layer.
stratum lamellatum
laminae of the hoof corium.
stratum lucidum
the translucent layer of the skin just beneath the stratum corneum. Called also clear layer. Present in the epidermis of the planum nasale of several species and footpads of carnivores.
stratum spinosum
the layer of the epidermis between the stratum granulosum and the stratum basale, marked by the presence of prickle cells; called also spinous layer and prickle-cell layer.
stratum tectorium
the layer of horny scales claimed to exist on the surface of the horse's hoof that gives it the smooth glossy appearance.
References in periodicals archive ?
The delivery system for Strivectin neck cream is created by an emulsion which includes fatty acids and fatty acid esters that increase the fluidity of the stratum corneum and by a pH that is slightly acidic, which keeps the polypeptides and amino acids in a neutral electrical charge, according to Nathalie Chevreau, director of women's health, Klein-Becker.
For example, atopic dermatitis is characterized by reduced ceramide concentrations in the stratum corneum.
1989) Antimicrobial activity of stratum corneum lipids from normal and essential fatty acid-deficient mice.
Menthol affects skin permeation by a dual mechanism: by forming a eutectic mixture with the penetrating compound, thereby increasing its solubility, and by altering the barrier properties of the stratum corneum (9).
The reason behind this could be that, once an iontophoretic diffusion path through the stratum corneum of the skin has been established, the current profile doesn't govern the flow rate of the drug.
The granular layer produces protein and lipids (fat) for the stratum corneum.
Immunolocalization of stratum corneum chymotryptic enzyme in human skin and oral epithelium with monoclonal antibodies: evidence of a proteinase specifically expressed in keratinizing squamous epithelia.
The barrier faced by investigators pursuing the idea has been the stratum corneum, a dense layer of dead cells that forms the outermost layer of skin.
Journal of Drugs in Dermatology recently published the results of two randomized, controlled studies evaluating the stratum corneum (skin barrier) integrity and skin hydration benefits of a variety of moisturizers containing various levels of oils/lipids (e.
In particular explaining to parents that although structurally similar both the epidermis and, the stratum corneum, are 20% and 30% thinner than that of an adult, which makes infant skin more susceptible to skin problems (Stamatas et al, 2010).
Those are also anticipated to remain on the upper stratum corneum and not penetrate beyond it.
But growth of transdermal delivery has been restricted by the need to limit candidate drugs to molecules small enough to effectively pass through the stratum corneum, a limitation that excludes passive transdermal patches as a viable option for the growing number of protein and peptide therapeutic compounds that will represent an increasing share of future NCEs.

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